Does tocilizumab have an effect on the clinical outcomes in COVID-19 patients? A meta-analysis of randomized control trials

Figures & data

Fig. 1 The search outputs and study selection

Table 1 The characteristics of included studies

Fig. 2 The effect of tocilizumab (Actemra) on the occurrence of death in patients with COVID-19

Fig. 3 The funnel plot (for assessing heterogeneity) and L’Abbe plot (for assessing heterogeneity)

Fig. 4 The effect of tocilizumab (Actemra) on the occurrence of ICU admission and need to ventilator in patients with COVID-19 (forest and funnel plot)

Table 2 The effect of presence non-communicable diseases on the prescript of tocilizumab in patients with COVID-19

Fig. 5 Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies

Fig. 6 Risk of bias summary: review authors' judgements about each risk of bias item for each included study

Availability of data and materials

The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.