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Lupus clinical development: will belimumab's approval catalyse a new paradigm for SLE drug development?

, PhD & , BS

Figures & data

Figure 1. Bull's eye chart summary of drugs in current systemic lupus erythematosus clinical trials.

Figure 1. Bull's eye chart summary of drugs in current systemic lupus erythematosus clinical trials.

Table 1. Drugs and sponsors in Phase II – III development for lupus sorted by MOA/therapeutic class.

Figure 2. Trial counts for ongoing and planned systemic lupus erythematosus trials by drug mechanism of action are shown.

Figure 2. Trial counts for ongoing and planned systemic lupus erythematosus trials by drug mechanism of action are shown.

Figure 3. Clinical end points under evaluation in ongoing and planned systemic lupus erythematosus trials are shown.

Figure 3. Clinical end points under evaluation in ongoing and planned systemic lupus erythematosus trials are shown.

Figure 4. Trial outcomes reported for completed Phase II and Phase III systemic lupus erythematosus trials by drug mechanism of action are shown.

Figure 4. Trial outcomes reported for completed Phase II and Phase III systemic lupus erythematosus trials by drug mechanism of action are shown.

Table 2. Forecasted completion dates of planned and ongoing industry-sponsored Phase II – III programs in lupus.

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