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Editorials

Endocannabinoid signaling in female reproductive events: a potential therapeutic target?

(Professor)

Figures & data

Table 1. Δ9-Tetrahydrocannabinol, endocannabinoids and major eCB system elements in female reproductive cells.

Figure 1. Illustration showing the localization of the main ECS elements in reproductive cells.

Figure 1. Illustration showing the localization of the main ECS elements in reproductive cells.

Table 2. Involvement of eCB system elements in female fertility. See text for details.

Figure 2. FAAH is a molecular integrator of female fertility signals. Compounds that act at the immune interface as pro-fertility signals (e.g., progesterone, leptin or T helper 2 [Th2] cytokines) also enhance FAAH activity. Conversely, molecules that can impair reproduction by acting on immune cells (e.g., Th1 cytokines) or on the uterine epithelium (e.g., progesterone and estrogen) inhibit FAAH.

Figure 2. FAAH is a molecular integrator of female fertility signals. Compounds that act at the immune interface as pro-fertility signals (e.g., progesterone, leptin or T helper 2 [Th2] cytokines) also enhance FAAH activity. Conversely, molecules that can impair reproduction by acting on immune cells (e.g., Th1 cytokines) or on the uterine epithelium (e.g., progesterone and estrogen) inhibit FAAH.

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