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Editorial

Combining glucose monitoring and insulin delivery into a single device: current progress and ongoing challenges of the artificial pancreas

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Figures & data

Figure 1. Schematic of approaches to an artificial pancreas. A broad spectrum of automated insulin delivery systems is under development, ranging from insulin suspension for reaching or approaching hypoglycemia, through night-time only closed-loop (CL) to full-day CL. Some systems retain the requirement for manual insulin dosing for meals (HCL), whereas others are fully automated. Finally, systems may include insulin only (Unihorm) or may incorporate other hormones (Bihorm). As these systems increase in automation and complexity, the need for user input decreases, but may be met by a compensatory increase in challenge to commercialization.

Figure 1. Schematic of approaches to an artificial pancreas. A broad spectrum of automated insulin delivery systems is under development, ranging from insulin suspension for reaching or approaching hypoglycemia, through night-time only closed-loop (CL) to full-day CL. Some systems retain the requirement for manual insulin dosing for meals (HCL), whereas others are fully automated. Finally, systems may include insulin only (Unihorm) or may incorporate other hormones (Bihorm). As these systems increase in automation and complexity, the need for user input decreases, but may be met by a compensatory increase in challenge to commercialization.

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