Figures & data
Fetal glucocorticoid overexposure (exogenous administration of glucocorticoids or inhibition of feto-placental 11b-HSD2 activity), in combination with genetic factors, will influence the development of many organ systems, and program tissue responses in the developing offspring, leading to adult disorders.
![Figure 1. Glucocorticoid hormone programming in early-life and its impact on adult health.Fetal glucocorticoid overexposure (exogenous administration of glucocorticoids or inhibition of feto-placental 11b-HSD2 activity), in combination with genetic factors, will influence the development of many organ systems, and program tissue responses in the developing offspring, leading to adult disorders.](/cms/asset/9d95e0b0-ee27-4e97-81e3-52f55cc77ff5/iere_a_11207396_f0001_b.jpg)