Notes
Sources: Franciosi LG, Diamant Z, Banner KH. Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials. Lancet Respir. Med. 1(9), 714–727 (2013); Verona Pharma News: www.veronapharma.com/joomla/images/Lancet_RM_publication_25Oct2013.pdf