Abstract
Ocular candidiasis is a common cause of endogenous fungal endophthalmitis and can also occur in the postoperative setting. The diagnosis of ocular candidiasis is usually made on clinical grounds but microbiological cultures are helpful to establish the identity of the infecting organism and determine the antimicrobial sensitivities. It is likely that PCR technology will become more important in the near future for rapid identification of infecting organisms, as it is applicable to both anterior chamber fluid and vitreous sampling. Furthermore, PCR has the potential to assist in directing antifungal therapy. There are many different antifungal agents in clinical use. Recent studies of newer antifungals, such as voriconazole, show significant potential for their use in the treatment of intraocular infections. Vitrectomy may provide benefit in cases presenting with severe vitritis at presentation or in cases with mild vitritis unresponsive to medical therapy.
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.