Advanced search
Publication Cover
Expert Review of Proteomics Volume 6, 2009 - Issue 3
Submit an article Journal homepage
1,376
Views
26
CrossRef citations to date
0
Altmetric
Editorial

Preparing multiple-reaction monitoring for quantitative clinical proteomics

Kyunggon Kim Department of Biomedical Sciences, Seoul National University College of Medicine, 28 Yongon-Dong, Seoul 110-799, Korea
&
Youngsoo Kim Department of Biomedical Science and Cancer Research Institute, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Ku, Seoul 110-799, Korea. [email protected]
Pages 225-229 | Published online: 09 Jan 2014

Figures & data

Figure 1. Multiple-reaction monitoring (MRM) applied to early cancer diagnosis.

One MRM run per patient blood sample can measure many cancer biomarkers at the same time. MRM assays use less than 20 µl of blood.

AFP: α-fetoprotein; BTA: Bladder tumor antigen; CEA: Carcinoembryonic antigen; NSE: Neuron-specific enolase; PSA: Prostate-specific antigen.

Figure 1. Multiple-reaction monitoring (MRM) applied to early cancer diagnosis.One MRM run per patient blood sample can measure many cancer biomarkers at the same time. MRM assays use less than 20 µl of blood.AFP: α-fetoprotein; BTA: Bladder tumor antigen; CEA: Carcinoembryonic antigen; NSE: Neuron-specific enolase; PSA: Prostate-specific antigen.
Figure 2. Effect of drug treatment, modeled as the flux of targeted proteins in blood.

MRM: Multiple-reaction monitoring.

Figure 2. Effect of drug treatment, modeled as the flux of targeted proteins in blood.MRM: Multiple-reaction monitoring.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related Research Data

Using data-independent, high-resolution mass spectrometry in protein biomarker research: perspectives and clinical applications.
Source: Wiley
Targeted proteomics for quantification of histone acetylation in Alzheimer's disease.
Source: Wiley

Linking provided by 

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.