Percutaneous coronary intervention in diabetic patients: should choice of stents be influenced?

Abstract

Patients with diabetes mellitus are prone to a diffuse and rapidly progressive form of coronary artery disease. As a result, diabetic patients undergoing coronary revascularization are at higher risk of cardiovascular events compared with nondiabetic patients. Due to marked advances of stent device technology and adjunctive pharmacology, percutaneous coronary intervention has been regarded as an efficient revascularization strategy in diabetic patients. Numerous randomized trials and large observational registries have compared the efficacy and safety of bare-metal stents and drug-eluting stents, as well as several DE platforms. This article systematically reviews the cumulative evidence from key clinical studies and tries to help guide the physician in making informed decisions on the optimal stent type for patients with diabetes mellitus.

Keywords::

• coronary artery disease
• coronary stents
• diabetes mellitus
• drug-eluting stents
• mortality • stent thrombosis

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.