Figures & data
The dependence is plotted with different levels of vaccine efficacy against carriage progression to disease (VEP = 90, 80, 70, 60, 50, 40, 30 and 0% from top to bottom). For smaller values of VEp, the lines are steeper, indicating a larger predictive value of carriage as marker of the direct protection against disease in the individual (see text). VEacq: Vaccine efficacy against acquisition; VED: Vaccine efficacy against disease; VEp: Vaccine efficacy against carriage progression to disease.
![Figure 1. Dependence of vaccine efficacy against disease on vaccine efficacy against acquisition.The dependence is plotted with different levels of vaccine efficacy against carriage progression to disease (VEP = 90, 80, 70, 60, 50, 40, 30 and 0% from top to bottom). For smaller values of VEp, the lines are steeper, indicating a larger predictive value of carriage as marker of the direct protection against disease in the individual (see text). VEacq: Vaccine efficacy against acquisition; VED: Vaccine efficacy against disease; VEp: Vaccine efficacy against carriage progression to disease.](/cms/asset/a556882a-6971-4a85-a6fd-69fbc79f5b53/ierv_a_11217729_f0001_b.jpg)