Figures & data
Table 1. Primers sequences.
Table 2. siRNA sequences.
Figure 2. Interactions and silencing efficacy of the targeted genes.
(A) Protein–protein interaction using STRING database, the PPI enrichment p-value: 0.0681. (B) Relative normalized expression of Notch1 siRNA, ANGPTL4 siRNA, NF-κβ1 siRNA in cells transfected with 100 nM siRNA targeting each gene's mRNA. The results normalized to scrambled-siRNA.
n = 3, values are (mean ± SD).
![Figure 2. Interactions and silencing efficacy of the targeted genes.(A) Protein–protein interaction using STRING database, the PPI enrichment p-value: 0.0681. (B) Relative normalized expression of Notch1 siRNA, ANGPTL4 siRNA, NF-κβ1 siRNA in cells transfected with 100 nM siRNA targeting each gene's mRNA. The results normalized to scrambled-siRNA.n = 3, values are (mean ± SD).](/cms/asset/4de981cc-0b5e-422b-aa0c-885986309b46/ifso_a_2341565_f0002_c.jpg)
Figure 3. The dose-dependent assay for siRNAs (Notch1, scrambled (SC), ANGPLT4 and NF-κβ1) from left to right, respectively.
siRNAs compared with mocked transfected PANC-1 cell line. Significant differences compared with SC siRNA.
***p < 0.001; ****p < 0.0001.
n = 3, values are (mean ± SD); ns: Not significant.
![Figure 3. The dose-dependent assay for siRNAs (Notch1, scrambled (SC), ANGPLT4 and NF-κβ1) from left to right, respectively.siRNAs compared with mocked transfected PANC-1 cell line. Significant differences compared with SC siRNA.***p < 0.001; ****p < 0.0001.n = 3, values are (mean ± SD); ns: Not significant.](/cms/asset/65d4b4a2-72c3-4aec-b7da-9b122a0964d4/ifso_a_2341565_f0003_c.jpg)