Validating LENT score in malignant pleural effusion

Figures & data

Figure 1. Median survival in days according to type of malignancy.

Table 1. Baseline characteristics.

Variable	Absolute n (%)
Age (years)	Mean 54.15 years, range 18–85 years
Gender   Male   Female	71 (35.1%) 131 (64.9%)
Laterality   Left   Right   Bilateral	89 (44.05%) 85 (42.07%) 28 (13.86%)
Smoking status   Smokers   Non-smokers   Missing	20 (9.9%) 72 (35.64%) 110 (54.45%)
Mode of diagnosis Pleural cytology, flow cytometry or pleural biopsy Otherwise unexplained effusion with confirmed malignancy elsewhere	64 (31.6%) 138 (68.3%)

Table 2. Distribution of LENT categories and median survival.

LENT Category	Count	Percent	Median survival (months)
Low risk	5	4.2%	9.41
Moderate risk	61	50.8%	5.36
High risk	54	45.0%	0.55
Overall median survival			2.06

Figure 2. Survival functions according to LENT score (low, moderate and high) risk.

Figure 3. Bar chart of mortality versus LENT score (low, moderate, high) risk.

(A) 1-month mortality, (B) 3-month mortality (C) 6-month mortality.

Figure 4. ROC curve for LENT score for the outcome of mortality.

At (A) 1-month mortality (B) 3-month mortality (C) 6-month time periods. AUC was 0.74, 0.78 and 0.79, respectively. All p-values <0.001.

Table 3. Predicted death probability for LENT scores; 1 month, 3 months and 6 months mortality groups.

Groups	Low LENT risk score	Moderate LENT risk score	High LENT risk score
1 months	0.039	0.223	0.670
3 months	0.036	0.289	0.818
6 months	0.054	0.467	0.930