Figures & data
Table 1 Demographic characterization of patients with pathogenic/likely pathogenic variants in FTLD-associated genes at UCSF and commercial clinical laboratory
Figure 1 GRN variants in cohorts from UCSF and a Commercial Clinical Laboratory.
Abbreviation: UCSF, University of California, San Francisco.
![Figure 1 GRN variants in cohorts from UCSF and a Commercial Clinical Laboratory.](/cms/asset/b1dcb421-0547-487d-b1fd-e6a99ee3f4e9/dagg_a_12191615_f0001_c.jpg)
Figure 2 Neuroimaging from select GRN variant cases.
Abbreviations: CDR, clinical dementia rating; R, right; L, left.
![Figure 2 Neuroimaging from select GRN variant cases.](/cms/asset/1b96ea1c-ee65-4a6e-af41-ebc962d301b0/dagg_a_12191615_f0002_b.jpg)
Table S1 Transcript IDs
Table S2 GRN variants included in this study; count in the commercial clinical laboratory/UCSF cohort and overall ExAC frequenciesa
Table S3 Pathogenic/likely pathogenic MAPT variants included in this study; count in commercial clinical laboratory/UCSF cohort and overall ExAC frequenciesa
Table S4 Type and quantity of overlap in MAPT and GRN variants between cohorts from UCSF and a commercial clinical laboratory
Figure S1 Selection of participants from UCSF.
Abbreviations: UCSF, University of California, San Francisco; FTLD, frontotemporal lobar degeneration.
![Figure S1 Selection of participants from UCSF.](/cms/asset/125742fc-b6b9-452f-81b0-c48ef36c7ea5/dagg_a_12191615_sf0001_c.jpg)
Figure S2 Selection of participants from a commercial clinical laboratory.
Abbreviation: FTLD, frontotemporal lobar degeneration.
![Figure S2 Selection of participants from a commercial clinical laboratory.](/cms/asset/4cf67ddc-8361-4380-8a08-b03bd1ee0271/dagg_a_12191615_sf0002_c.jpg)