Figures & data
Figure 1 Heat map of TRP channel expression in 11 native human breast cancer tissues and four healthy breast tissues.
Abbreviations: CCG, Cologne Center for Genomics; FPKM, fragments per kilobase of exon per million fragments mapped; TRP, transient receptor potential.
![Figure 1 Heat map of TRP channel expression in 11 native human breast cancer tissues and four healthy breast tissues.](/cms/asset/373cc488-8d6f-4f69-8f27-986a4febc1da/dbct_a_28008282_f0001_c.jpg)
Figure 2 Heat map of TRP channel expression in 49 breast cancer cell lines and healthy tissues.
Abbreviations: FPKM, fragments per kilobase of exon per million fragments mapped; TRP, transient receptor potential.
![Figure 2 Heat map of TRP channel expression in 49 breast cancer cell lines and healthy tissues.](/cms/asset/80f07f42-f23a-43c8-8d84-26c89c045c31/dbct_a_28008282_f0002_c.jpg)
Figure 3 Expression of TRPV1 in breast cancer tissues and cell lines.
Abbreviations: BC, breast cancer; M, marker; PCR, polymerase chain reaction; RT, reverse transcriptase; TNBC, triple-negative breast cancer.
![Figure 3 Expression of TRPV1 in breast cancer tissues and cell lines.](/cms/asset/738c8c33-33c0-4141-b223-07530da42d51/dbct_a_28008282_f0003_c.jpg)
Figure 4 Expression profiles of TRP channels in the SUM149PT breast cancer cell line.
Abbreviations: DAPI, 4′,6-diamidino-2-phenylindole; M, marker; NGS, next-generation sequencing; PCR, polymerase chain reaction; RT, reverse transcriptase; TRP, transient receptor potential.
![Figure 4 Expression profiles of TRP channels in the SUM149PT breast cancer cell line.](/cms/asset/dfa077a1-3450-4bf2-aaf7-a19cc2389336/dbct_a_28008282_f0004_c.jpg)
Figure 5 Functional characterization of TRPV1 activation by capsaicin in SUM149PT cells.
Abbreviations: C, capsaicin; CZ, capsazepin; FITC, fluorescein isothiocyanate; PI, propidium iodide; F340/F380, ratio of the fluorescence intensities at 340 nm and 380 nm excitation; C, capsaicin; CZ, capsazepin; ATP, adenosine triphosphate; ns, not significant.
![Figure 5 Functional characterization of TRPV1 activation by capsaicin in SUM149PT cells.](/cms/asset/21dc0e7e-27ad-4b69-b02a-ac11b263cf8f/dbct_a_28008282_f0005_c.jpg)