Breast cancer prevention in older women: an algorithm to choose an optimal preventive agent

Figures & data

Figure 1 Chemopreventive choice optimization algorithm.

Note: Solid lines indicate strong evidence is present. Dotted lines indicate weaker evidence is present for this recommendation.
Abbreviations: AI, aromatase inhibitor; DEXA, dual-energy x-ray absorptionmetry; GRI, Gail risk index; SERM, selective estrogen receptive modulator; TE, thromboembolic event.

Figure 2 Treatment processes.

Figure 3 Reasons to discontinue medication.

Table 1 Clinical characteristics of patients

Age	Mean=72.6 years (range 59–80 years)
Common comorbid diseases	Number
Osteoporosis (Y/N)	4/19
HTN (Y/N)	19/4
DM (Y/N)	10/13
CAD (Y/N)	3/20
Active smoker (Y/N)	0/23
Hysterectomy status (Y/N)	14/9
BMI	M=32.9 kg/m^2 (range 20.6–39 kg/m^2)

Abbreviations: BMI, body mass index; CAD, coronary artery disease, DM, diabetes mellitus; HTN, hypertension; M, median; N, no; Y, yes.