Figures & data
Figure 1 Structure and functions of WASP/WAVE family proteins.
Notes: (A) Metastatic cascade showing the role of migration and invadopodia in successful invasion, intravasation, and extravasation of the tumor cell from the primary breast tumor to secondary foci, eg, the lung. (B) The structure and functional motifs for nWASP and WAVE and the interactions between them. They are related to the functions of both these proteins in the control of the actin cytoskeleton and hence the migratory capacity of cells.
