Paradoxical SAPHO syndrome observed during anti-TNFα therapy for Crohn’s disease

Figures & data

Figure 1 (A) Acne in right lower limb, which spread to patient’s face, limbs, and trunk; (B, C) palmoplantar pustulosis.

Figure 2 Computed tomography scan of clavicles. Erosion in right clavicle (white arrow).

Figure 3 Bone-scintigraphy findings showed intensive uptake of ^99mTc at the sternoclavicular joints and sternum, called a “bull’s head” sign.