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Literature Review

Ovarian cancer: emerging molecular-targeted therapies

Pages 147-154 | Published online: 20 Jun 2012

Figures & data

Figure 1 Targeting ovarian cancer cells.

Notes: Emerging molecular-targeted agents affect aberrant biological functions of a cancer cell. As depicted in this figure, targeting one or several of those functions might significantly improve the outcomes for women with ovarian cancer.
Abbreviations: PTHrP, parathyroid hormone related protein; VEGF, vascular endothelial growth factor; Glut1, glucose transporter 1; NFkB, nuclear factor-kB; EGFR, epidermal growth factor receptor; PI3K, phosphoinositide-3-kinase; PARP, poly (ADP-ribose) polymerase; HIF, hypoxia inducible factor.
Figure 1 Targeting ovarian cancer cells.