Figures & data
Figure 1 Pathophysiology of giant-cell tumor of bone.
Abbreviation: RANKL, receptor activator of nuclear factor-κB ligand; SDF-1, Stromal cell-derived factor 1; MCP-1, Monocyte Chemoattractant Protein-1; OPG, osteoprotegrin; TRAP, tartrate resistant acid phosphatase; RANK, receptor activator of NF-kappaB.
![Figure 1 Pathophysiology of giant-cell tumor of bone.](/cms/asset/3e7a84ec-66ee-4c32-a3f7-6c39d4885f3e/dbtt_a_57359_f0001_c.jpg)
Table 1 Systemic therapies for giant-cell tumor of bone (GCTB)