Clinical effects of an oral supplement rich in antioxidants on skin radiance in women

Figures & data

Table 1 Clinical descriptors evaluated by C.L.B.T.™ and imperfections scale

Abbreviations: C.L.B.T., coloring, luminosity, brightness, and transparency; Min, minimum; Max, maximum.

Figure 1 Evaluation of the C.L.B.T.^™ parameters before and after supplementation.

Notes: (A) Red pink and olive color decrease significantly (***P<0.0001). Beige color is not significantly altered as the change of deviation from the optimal value 50 is not modified after the supplementation. (B) Luminosity is significantly increased at the end of the supplementation compared to the baseline (***P<0.0001). (C) Brightness decreases at T8 compared to the baseline (*P<0.05). (D) Transparency increases slightly but not significantly at T8.
Abbreviations: C.L.B.T., coloring, luminosity, brightness, and transparency; T0, Time 0, baseline; T8, Time 8, eight weeks.

Figure 2 Evaluation of the facial skin imperfections before and after supplementation.

Notes: (A) Dark circles relief and color are reduced after supplementation compared to baseline (**P<0.01; ***P<0.0001), (B) redness is also reduced at T8 compared to baseline T0 (***P<0.0001), and (C) spots are decreased after supplementation (***P<0.0001). (D) Complexion heterogeneity is not modified by the supplementation. (E) The global imperfection score (dark circles relief and color + redness/rosacea + spots + heterogeneity scores) decreased by 18% (***P<0.0001).
Abbreviations: T0, Time 0, baseline; T8, Time 8, eight weeks.

Table 2 Firmness evaluation by clinical examination

Firmness	T0		T8*
	n	%	n	%
Absent–Light	16	47.1	8	23.5
Moderate–Important	18	52.9	26	76.5

Note: Population repartition was significantly different between T0 and T8 switching from the “Absent–Light” to the “Moderate–Important” category of firmness (*P<0.05).

Abbreviations: T0, Time 0, baseline; T8, Time 8, eight weeks.

Figure 3 Evaluation of the skin elasticity by cutometer.

Note: Elasticity, represented by the ratio Ur/Ue, increases reflecting a better skin elasticity (*P<0.05).
Abbreviations: Ue, U extensibility; Ur, immediate retraction; T0, Time 0, baseline; T8, Time 8, eight weeks.

Table 3 Auto-evaluation of skin parameters at T0 and T8

Questions	T0	T8		P-value (T8 vs T0)	Evolution (%)	Women with positive evolution (%)	Evolution in women with positive score (%)
For you, the radiance of your complexion is? (0= dull – >10= glowing)	4.0±0.3	5.1±0.3	**	<0.01	28.9	76.5	62.3
Is your complexion fresh? (0= not – >10= very)	3.9±0.2	5.3±0.3	***	<0.0001	35.9	79.4	52.6
Is your complexion luminous? (0= not – >10= very)	3.8±0.3	5.0±0.3	**	<0.01	30.6	70.6	69.4
Is your complexion homogeneous? (0= not – >10= very)	3.2±0.4	4.3±0.4	**	<0.01	37.2	67.6	101.0
Is your skin smooth? (0= not – >10= very)	4.4±0.4	5.2±0.3	*	<0.05	18.7	61.8	52.3
Is your skin texture refined? (0= not refined – >10= very refined)	4.7±0.4	5.2±0.3	NS	0.1598	8.7	66.7	37.7
Is your skin firm? (0= soft – >10= firm)	3.7±0.3	4.4±0.3	*	<0.05	19.5	67.6	55.8
Is your skin hydrated? (0= not – >10= very)	4.4±0.3	4.8±0.3	NS	0.2365	9.6	58.8	45.9

Notes:

* P<0.05;

** P<0.01;

*** P<0.001.

Abbreviations: NS, not significant; T0, Time 0, baseline; T8, Time 8, eight weeks.

Table 4 Auto-evaluation after the supplementation: satisfaction questions

Satisfaction questions
Do you think you look better?	No	Yes
	35.3% (n=12)	64.7% (n=22)
How do you estimate the global efficacy of the dietary supplement?	None	Moderate to very good
	17.6% (n=6)	82.4% (n=28)