Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium

Figures & data

Table 1 Percentage of participants with some improvement under items evaluated in both groups after 90 days (n=92)

D90	Hair loss		Hair volume		Density of hair		Quality of hair		Hair shine		Hair strength
	I	II	I	II	I	II	I	II	I	II	I	II
Clinical improvement (%)	76.6	60.0	51.0	42.2	48.9	33.3	53.1	40.0	36.1	22.2	40.4	31.1
P-value	<0.001a	<0.001a	<0.001a	0.003a	<0.001a	0.014a	<0.001a	0.016a	0.042a	0.856	0.008a	0.076

Notes:

a Level of significance of 5%. Hypothesis: non-inferiority between treatments.

Abbreviations: I, group treated with Eximia Fortalize Kera D^®; II, group treated with comparator; D90, 90-day evaluation.

Table 2 Percentage of participants with some improvement under items evaluated in both groups after 180 days (n=92)

D180	Hair loss		Hair volume		Hair density		Quality of hair		Hair shine		Hair strength
	I	II	I	II	I	II	I	II	I	II	I	II
Clinical improvement (%)	87.2	82.2	59.5	53.3	59.5	55.5	72.3	51.1	59.5	40.0	70.2	53.3
P-value	<0.001a	<0.001a	<0.001a	<0.001a	<0.001a	<0.001a	<0.001a	<0.001a	<0.001a	0.005a	<0.001a	<0.001a

Notes:

a Level of significance of 5%. Hypothesis: non-inferiority between treatments.

Abbreviations: I, group treated with Eximia Fortalize Kera D^®; II, group treated with comparator; D180, 180-day evaluation.

Table 3 Hair density represented by number of counted hairs in standard area

	Initial assessment		D90		D180
	I	II	I	II	I	II
Mean	235.41±59.99	242.88±71.46	232.88±66.04 (0.747%)	251.89±86.03 (3.71%)	263.44±89.62 (11.09%)a	261.73±89.67 (7.76%)

Notes:

a Level of significance of 5%. Hypothesis: non-inferiority among treatments.

Abbreviations: I, group treated with Eximia Fortalize Kera D^®; II, group treated with comparator; D90, 90-day evaluation; D180, 180-day evaluation.

Table 4 Comparison by Mann–Whitney U test between groups 1 and 2 in D90 in relation to D0 (n=92)

Subjective parameters	I (%)	II (%)	P-value
Hair loss improvement	70.22	77.78	0.109
Hair shine	59.58	53.33	0.330
Hair strength	78.72	57.78	0.022a
Convenience of use in terms of the amount of tablets/capsules ingested per day	91.48	74.34	0.012a
Ease of swallowing of tablets/capsules	82.98	86.67	0.706
Absence of residual taste from tablets/capsules	72.34	40.00	0.001a

Notes:

a Level of significance of 5%. Hypothesis: non-inferiority among treatments.

Abbreviations: I, group treated with Eximia Fortalize Kera D^®; II, group treated with comparator; D90, 90-day evaluation; D0, initial time.

Table 5 Comparison by Mann–Whitney U test between groups 1 and 2 at D180 in relation to D0 (n=92)

Subjective parameters	I (%)	II (%)	P-value
Hair loss improvement	82.98	80.00	0.866
Hair shine	76.60	77.78	0.940
Hair strength	80.85	84.44	0.346
Convenience of use in terms of the amount of tablets/capsules ingested per day	93.62	67.78	0.006a
Ease of swallowing of tablets/capsules	85.11	88.89	0.829
Absence of residual taste from tablets/capsules	74.47	66.22	0.214

Notes:

a Level of significance of 5%. Hypothesis: non-inferiority among treatments.

Abbreviations: I, group treated with Eximia Fortalize Kera D^®; II, group treated with comparator; D0, initial time; D180, 180-day evaluation.