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Original Research

Genetic polymorphism analysis of patients with primary hyperhidrosis

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Pages 477-483 | Published online: 11 Oct 2018

Figures & data

Figure 1 Idiogram of Chromosome 3 – BCHE gene on 3q26.1.

Abbreviation: BCHE, Butyrylcholinesterase.
Figure 1 Idiogram of Chromosome 3 – BCHE gene on 3q26.1.

Figure 2 BCHE K-variant – The alanine nucleotide is replaced by a threonine nucleotide at the 539 codon.

Abbreviation: BCHE, Butyrylcholinesterase.
Figure 2 BCHE K-variant – The alanine nucleotide is replaced by a threonine nucleotide at the 539 codon.

Figure 3 SNP visualization via clustered heatmap.

Notes: The box for each SNP position indicates whether the sample has the most common variation (gray) or any other variation (black).
Abbreviation: SNP, single-nucleotide polymorphism.
Figure 3 SNP visualization via clustered heatmap.

Figure 4 Allelic distribution sorted by SNP (including seven cases without a diagnosis of primary hyperhidrosis).

Note: The bar charts indicate overall counts of all variations broken down separately for case and control populations.
Abbreviation: SNP, single-nucleotide polymorphism.
Figure 4 Allelic distribution sorted by SNP (including seven cases without a diagnosis of primary hyperhidrosis).

Figure 5 Allelic distribution sorted by SNP (excluding seven cases without a diagnosis of primary hyperhidrosis).

Note: The bar charts indicate overall counts of all variations broken down separately for case and control populations.
Abbreviation: SNP, single-nucleotide polymorphism.
Figure 5 Allelic distribution sorted by SNP (excluding seven cases without a diagnosis of primary hyperhidrosis).

Table 1 Association of SNPs in the BCHE and CHRNA7 genes with hyperhidrosis