Topical effects of SCA^® (Cryptomphalus aspersa secretion) associated with regenerative and antioxidant ingredients on aged skin: evaluation by confocal and clinical microscopy

Figures & data

Table 1 Percentage of participants with perception of significant improvement (P<0.05; n=34)

Parameter	45-day evaluation (%)	90-day evaluation (%)
Hydration	58.2	64.7
Softness	55.8	64.7
Firmness	64.7	58.8
Elasticity	47.0	41.2
Expression lines	58.8	58.2
Luminosity	58.8	52.9
Grooves	38.2	44.1
Fine lines	50.0	52.9

Figure 1 Photographs of dermis with confocal reflectance microscopy.

Notes: (A) Initial. (B) After 90 days of use. Observe greater parallelism of more evident collagen fibers in B.

Table 2 Percentage of participants with perception of significant improvement (P<0.05; n=37)

Parameter	45-day evaluation (%)	90-day evaluation (%)
Hydration	55.4	70.2
Softness	56.7	78.3
Firmness	56.7	81
Elasticity	45.9	51.3
Expression lines	54	62.1
Luminosity	45.9	56.7
Grooves	54	67.5
Fine lines	48.6	54

Figure 2 Photographs of dermis with confocal reflectance microscopy.

Notes: (A) Initial. (B) After 90 days of use. Observe higher brightness suggesting the presence of more collagen fibers.

Table 3 Percentage of participants with a perception of significant improvement (P<0.05; n=36)

Parameter	45-day evaluation (%)	90-day evaluation (%)
Hydration	66.7	77.8
Softness	58.3	66.7
Firmness	58.3	80.5
Expression lines	38.8	52.7
Luminosity	47.2	66.7
Elasticity	47.2	61.1
Periorbital hyperchromia	38.8	63.8