Skin protective effects of an antipollution, antioxidant serum containing Deschampsia antartica extract, ferulic acid and vitamin C: a controlled single-blind, prospective trial in women living in urbanized, high air pollution area

Figures & data

Figure 1 Evolution of transepidermal water loss (TEWL). *P=0.002; Wilcoxon test.

Abbreviations: TEWL, Trans Epidermal Water Loss; D0, Day zero; D28, Day 28.

Figure 2 Evolution of dark spots evaluated with colorimetry; *P=0.0021; Wilcoxon test. Abbreviation: ITA, Individual Typology Angle.

Figure 3 Evolution of SQOOH/SQ ratio. *P=0.017; Wilcoxon test.

Abbreviations: SQOOH, Squalene peroxide; SQ, Squalene.

Figure 4 High-resolution pictures of two subjects evaluating dark spots (A and A1: baseline, D0; B and B1: after treatment D28).

Table 1 Subjects’ characteristics at baseline

Number	20
Mean age, years, mean±SD	42±7
Fitzpatrick photo type, %	I: 0% II:40% III:60%
Subjects with sensitive skin, n(%)	10 (50%)
Transepidermal water loss, (TEWL) g/m^2/hr, mean±SD	10.4±2

Table 2 Data analysis of outcomes variables

	Baseline	Day 28	Variation and P-value
Transepidermal water loss (TEWL: g/m^2/hr; mean±SD	10.4±1.99	8.3±1.3	−19.1% (<0.05)
Colorimetry (individual typology angle (ITA°); mean±SD	23.8±4.4	25.5±5.6	+7% (<0.05)
Squalene peroxided SQOOH/Squalene SQ %	12.7±7.6	9.0±5.6	−16% (<0.05)