Steroid-sparing effects and acceptability of a new skin gel containing the anti-inflammatory medicinal substance-nicotinamide

Figures & data

Table 1 DENI gel composition

DENI gel
Nicotinamide Liquid Paraffin Isopropyl Myristate
Glycerol
Carbomer
Sorbitan laurate
Triethanolamine
Phenoxyethanol
Purified Water

Figure 1 Clinical performance and acceptability of DENI gel.

Figure 2 Packaging acceptability.

Figure 3 Packaging leaflet acceptability.

Table 2 Part 1 - Skin condition frequency table

Skin Conditions Frequency Table
Skin Condition	No. Patients	%
Atopic dermatitis	4	8.3
Contact dermatitis	3	6.3
Eczema	16	33.3
Psoriasis	25	52.1
Total	48	100

Table 3 Part 2 - Skin condition frequency table

Skin Conditions Frequency Table
Skin Condition	No. Patients	%
Dermatitis	1	5
Eczema	9	45
Psoriasis	10	50
Total	20	100

Table 4 Part 2 - Emollients used

Emollients Used Frequency Table
Emollient Name	No. Patients*	%
Aveeno	8	40
Oilatum	4	20
Diprobase	3	15
Zerobase	2	10
E45	2	10
Doublebase	2	10
m-folia	1	5
Epaderm	1	5
Hydromol	1	5
Sudocrem	1	5
No emollient	2	10
Total	20	100

Note: *Some patients used more than one emollient.

Table 5 Part 2 - Other products used

Other Products Used to Treat Skin Condition Frequency Table
Product Class	No. Patients*	%
Topical Steroid	9	45
Immunomodulators	3	15
Vitamin D analogues	2	10
Vitamin D analogues / Corticosteroids (combination)	2	10
No other treatments	7	35
Total	20	100

Note: *Some patients used more than one additional product to treat their skin condition.

Figure 4 Q: Thinking about your skin condition and the effectiveness of treatment over the last four weeks, did you need to use less, about the same or more DENI gel than the amount of your usual emollient(s) which you would have expected to use? (n=19).

Figure 5 Q: Overall, would you say your skin condition has benefited from using DENI gel? (n=19).

Figure 6 Q: Did you apply DENI gel to all affected skin areas, or only to selected areas?

Figure 7 Q: Did you use DENI gel every day over the past four weeks, or just when you felt you needed it? (n=19).