Correlation Between Lipid Profile and Acne Vulgaris

Figures & data

Figure 1 Severity of acne among patients.

Table 1 Comparison of Lipid Profile of Male and Female Subjects in Patient and Control Groups

Parameters (mg/dL)	Male			Female			Total
	Acne Patients (Mean±SD)	Controls (Mean±SD)	P (t-Test)	Acne Patients (Mean±SD)	Controls (Mean±SD)	P (t-Test)	Acne Patients (Mean±SD)	Controls (Mean±SD)	P (t-Test)
TG	108.1±69.5	99.6±43.4	0.936	88.5±40.7	78.9±29.8	0.536	94.6±51.4	86.7±36.6	0.725
TC	173.9±30.1	150.3±3 0.3	0.04	156.8±24.9	145.3±26.3	0.157	162.1±27.5	147.2±27.6	0.025
LDL	100.3±22.6	93.4±32.4	0.330	83±18.8	82.8±21.2	0.891	88.3±21.4	86.8±26.2	0.608
HDL	47.5±9.6	45.3±10.8	0.425	53.2±13	48.7±10.6	0.171	51.4±12.2	47.4±10.7	0.110

Abbreviations: TG, triglycerides; TC, total cholesterol; LDL, low-density lipoprotein cholesterol; HDL, high-density lipoprotein cholesterol; SD, standard deviation.

Table 2 Comparison of Lipid Profile of Patients and Controls in Two Age Groups

Parameters (mg/dL)	<25 Years			≥25 Years
	Acne Patients (Mean±SD)	Controls (Mean±SD)	P (t-Test)	Acne Patients (Mean±SD)	Controls (Mean±SD)	P (t-Test)
TG	95.8±58.1	92.8±41.9	0.93	93.3±44.7	81.4±31.1	0.45
TC	160.8±22.1	150.1±30.1	0.16	163.4±32.7	144.6±25.6	0.07
LDL	88.2±17.8	88.5±28.6	0.78	88.5±25.1	85.3±24.5	0.74
HDL	49.9±13.3	47.3±11.4	0.39	53.2±13	48.7±10.6	0.13

Table 3 Lipid Profile Analysis in Different Severity of Acne

Parameters (mg/dL)	Acne severity			P (t-Test)
	Mild (Mean±SD)	Moderate (Mean±SD)	Severe (Mean±SD)
TG	76.1±22.3	106.1±61.9	87±41.6	0.502
TC	153.5±19.2	163.7±26.6	165.2±33.9	0.530
LDL	82.5±21.7	88.6±20.8	91.8±23.1	0.836
HDL	54±18.2	49.9±10.9	52.3±9.9	0.903

Table 4 Lipid Profile Analysis with Logistic Regression Model

Variable	Univariable				Multivariable
	OR	Exp(B)	Sig	95% CI	OR	Exp(B)	Sig	95% CI
TG	1.00	1.00	0.404	0.99–1.01	0.99	0.99	0.800	0.98–1.01
TC	1.02	0.05	0.016	1.00–1.03	1.05	1.04	0.007	1.01–1.09
LDL	1.00	0.70	0.756	0.98–1.02	0.95	0.96	0.020	0.92–0.99
HDL	1.03	0.15	0.108	0.99–1.07	1.00	1.01	0.805	0.95–1.06
Gender (female)	1.34	0.85	0.506	0.56–3.21	1.24	0.89	0.674	0.44–3.49
Age	1.00	0.723	0.838	0.93–1.08	0.99	1.00	0.834	0.91–1.07