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Original Research

Acne Vulgaris is Associated with the Human β-Defensin 1-Gene Polymorphisms in Han Chinese Ethnic Group Patients

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Pages 123-128 | Published online: 04 Feb 2021

Figures & data

Figure 1 Detection of human β-defensin-1 gene variations in the 5ʹ-UTR (G-52A, C-44G, and G-20A) by restriction enzyme digestion with NalV, HgaI, ScrFI, respectively, followed by 3% agarose gel electrophoresis. Lanes 1 AA genotype, lanes 2 GA genotype, lanes 3 GG genotype of SNP G-52A; lanes 4 CC genotype, lanes 5 CG genotype, lanes 6 GG genotype of SNP C-44G; and lanes 7 AA genotype, lanes 8 GA genotype, lanes 9 GG genotype of SNP G-20A. B is the blank comparison.

Abbreviation: M, maker.
Figure 1 Detection of human β-defensin-1 gene variations in the 5ʹ-UTR (G-52A, C-44G, and G-20A) by restriction enzyme digestion with NalV, HgaI, ScrFI, respectively, followed by 3% agarose gel electrophoresis. Lanes 1 AA genotype, lanes 2 GA genotype, lanes 3 GG genotype of SNP G-52A; lanes 4 CC genotype, lanes 5 CG genotype, lanes 6 GG genotype of SNP C-44G; and lanes 7 AA genotype, lanes 8 GA genotype, lanes 9 GG genotype of SNP G-20A. B is the blank comparison.

Table 1 Allele Distribution at the DEFB1 Locus in Acne Vulgaris and Control Groups (Numbers with Percentages in Parentheses)

Table 2 The Frequencies Distribution of DEFB1 Genotypes for the Acne Vulgaris Group and the Control Group (Numbers with Percentages in Parentheses)

Table 3 The Frequencies Distribution of DEFB1 Allele in the Control Group and the Acne Vulgaris Group (Numbers with Percentages in Parentheses)