Topical ALA-Photodynamic Therapy Combined with Acne Debridement and Meticulous Nursing for the Treatment of Moderate–Severe Acne in Adolescent Patients

Figures & data

Table 1 General Characteristic Comparison Between the Two Groups (x ± s), (n), and [n (%)]

Groups	Cases	Age	Gender		Types of Lesions			Course of Disease
			M	F	Papules	Pustules	Cysts	>1 Year	<1 Year
Observation group	30	16.40±1.28	3	27	11	8	2	18	12
Control group	30	16.60±1.33	2	28	10	7	3	16	14
χ^2/t		0.595	0.218		0.290			0.271
P		0.554	0.640		0.865			0.602

Table 2 Therapeutic Effect Comparison Between the Two Groups

Groups	Cases	Recovery	Markedly Effective	Effective	Invalid	Total Treatment Effectiveness
						Cases	%
Observation group	30	22	2	2	4	26	86.7
Control group	30	13	1	4	12	18	60

Figure 1 A female patient in control group: before treatment.

Figure 2 A female patient in control group: follow up 6 months after treatment.

Figure 3 A female patient aged 20 of the observed group. Frontal and bilateral clinical photos of the face before treatment.

Figure 4 A female patient aged 20 of the observed group. Frontal and bilateral clinical photos of the face 6 months after treatment.

Table 3 Adverse Reaction Incidence Comparison Between the Two Groups Three Days After Treatment

Groups	Cases	Erythema		Swelling		Itching		Total
		Cases	%	Cases	%	Cases	%	Cases	%
Observation group	30	0	0	1	3.3	5	16.7	6	20
Control group	30	5	16.7	5	16.7	7	23.3	17	56.7

Table 4 Postoperative VAS Comparison Between the Two Groups

Groups	Cases	VAS
		Immediately After Operation	30 min After the Operation	60 min After the Operation
Observation group	30	7.90±0.80	4.40±0.50	1.43±0.50
Control group	30	7.83±0.75	6.50±0.51	3.47±0.51
χ^2/t		0.333	16.155	15.572
P		0.740	<0.01	<0.01

Table 5 Patient Satisfaction Comparison Between the Two Groups

Groups	Cases	Very Satisfied		Satisfied		Dissatisfied		Satisfaction
		Cases	%	Cases	%	Cases	%	Cases	%
Observation group	30	25	83.3	2	6.7	3	1	27	90
Control group	30	17	56.7	3	13.3	10	30	20	70