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Original Research

Efficacy Evaluation of 755-nm Long-Pulse Alexandrite Laser Combined with 0.5% Timolol Maleate Eye Drops in the Treatment of Thicker Infantile Hemangioma

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Pages 1621-1628 | Published online: 09 Nov 2021

Figures & data

Table 1 Baseline Characteristics at Time of Inclusion

Figure 1 IH treatment with 755-nm long-pulse alexandrite laser combined with 0.5% timolol maleate eye drops. Patients and laser treatment situation: Patient 1: 6 months, male, B-ultrasound: 5mm, 3 times, 3ms, 40 J/cmCitation2. Patient 2: 5 months, female, B-ultrasound: 8mm, 6 times, 3ms, 45J/cmCitation2. Patient 3: 4 months, male, B-ultrasound: 7mm, 6 times, 3ms, 45J/cm2.

Figure 1 IH treatment with 755-nm long-pulse alexandrite laser combined with 0.5% timolol maleate eye drops. Patients and laser treatment situation: Patient 1: 6 months, male, B-ultrasound: 5mm, 3 times, 3ms, 40 J/cmCitation2. Patient 2: 5 months, female, B-ultrasound: 8mm, 6 times, 3ms, 45J/cmCitation2. Patient 3: 4 months, male, B-ultrasound: 7mm, 6 times, 3ms, 45J/cm2.

Table 2 The VAS at Each Time Point of IH in Different Thickness Groups

Figure 2 VAS at each time point of IH in different thickness groups treated with 755-nm long-pulse alexandrite laser combined with 0.5% timolol maleate eye drops.

Figure 2 VAS at each time point of IH in different thickness groups treated with 755-nm long-pulse alexandrite laser combined with 0.5% timolol maleate eye drops.

Table 3 Side Effects of 755-nm Long-Pulse Alexandrite Laser Combined with 0.5% Timolol Maleate Eye Drops in the Treatment of 74 Cases of IH

Figure 3 Patient 1 After 5 times of topical treatment with 755-nm long-pulse alexandrite laser combined with 0.5% timolol maleate eye drops, the pigmentation appeared, and the pigmentation subsided within 6 months of follow-up. Patient 2 After 755-nm long-pulse alexandrite laser combined with 0.5% timolol maleate eye drops for topical treatment for 6 times, hypopigmentation appeared and returned to normal within 6 months after the end of the treatment.

Figure 3 Patient 1 After 5 times of topical treatment with 755-nm long-pulse alexandrite laser combined with 0.5% timolol maleate eye drops, the pigmentation appeared, and the pigmentation subsided within 6 months of follow-up. Patient 2 After 755-nm long-pulse alexandrite laser combined with 0.5% timolol maleate eye drops for topical treatment for 6 times, hypopigmentation appeared and returned to normal within 6 months after the end of the treatment.