Successful Therapy of Alopecia Universalis Using a Combination of Systemic Methotrexate and Corticosteroids and Topical 5% Minoxidil

Figures & data

Figure 1 Comparison of alopecia universalis in a 19-year-old male patient before and after 3, 6, and 9 months systemic therapy of methotrexate (15 mg per week orally) and corticosteroids (16 mg per day orally) with topical minoxidil 5% showed hair growth on the scalp. The SALT score was improved from 100% (before treatment) became 41% (9 months after treatment).

Figure 2 Trichoscopic examination of the alopecia area on the scalp shows short vellus hairs in white colour before treatment. Three months after treatment, white and black short vellus hairs had growth, and after 6 and 9 months of treatment, trichoscopy examination result showed growth of terminal hair and getting evident.