A Randomized, Double Blinded, Split-Face Study of the Efficacy of Using a Broad Spectrum Sunscreen with Anti-Inflammatory Agent to Reduce Post Inflammatory Hyperpigmentation After Picosecond Laser

Figures & data

Table 1 Baseline Demographics of Enrolled Patients

Clinical Characteristics (n=Number of Patients)	(n =59)
Age (years)
Mean (SD)	28.56	±6.17
Gender, n (%)
Female	42	(71.2)
Male	17	(28.8)
Skin phototype, n (%)
Type III	33	(55.9)
Type IV	26	(44.1)
Baseline acne grade, n (%)
Mild	26	(44.1)
Moderate	33	(55.9)
Baseline acne scar grade, n (%)
Mild	31	(52.5)
Moderate	28	(47.5)

Table 2 Mean Brown Score at Baseline, Week 1, Week 2, Week 4 and Week 6 Follow-Up Visit

Week	Sunscreen A				Sunscreen B				P-value
	Mean Brown Score	SD	Mean Change from Baseline	P-value (Compare to Baseline)	Mean Brown Score	SD	Mean Change from Baseline	P-value (Compare to Baseline)
0	35.69	5.81			35.83	5.12			0.886
1	35.24	5.58	−0.42	0.312	35.46	5.25	−0.20	0.416	0.824
2	35.54	5.36	−0.14	0.743	35.89	5.25	0.05	0.904	0.720
4	35.32	5.43	−0.37	0.373	36.08	5.36	0.20	0.573	0.449
6	35.36	5.98	−0.24	0.491	35.69	5.42	−0.03	0.721	0.758

Figure 1 (A) Mean brown score (B) Mean porphyrins count (C) Mean change of inflammatory acne lesion counts (D) Mean change of non-inflammatory acne lesion counts at baseline, week 1, week 2, week 4 and week 6 follow-up visit. (***P < 0.05, compared between two products, *P < 0.05, compared with baseline).

Figure 2 Postoperatively treated side with the sunscreen A. (A) Baseline, (B) 1-week 1, (C) 2-week, (D) 4-week, and (E) 6-week follow-up visit.

Figure 3 Postoperatively treated side with the sunscreen B. (A) Baseline, (B) 1-week 1, (C) 2-week, (D) 4-week, and (E) 6-week follow-up visit.