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REVIEW

Augmented Glutathione Absorption from Oral Mucosa and its Effect on Skin Pigmentation: A Clinical Review

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Pages 1853-1862 | Received 14 Jun 2022, Accepted 12 Aug 2022, Published online: 10 Sep 2022

Figures & data

Figure 1 Melanin synthesis (Raper–Mason pathway). Role of glutathione in shifting the equation of melanin synthesis from eumelanin to pheomelanin.

Abbreviations: DHI, 5,6-dihydroxyindole; L-DOPA, Levo DOPA; DOPA, 3,4-dihydroxyphenyl alanine; DHICA, 5,6-dihydroxyindole-2-carboxylic acid; GST, glutathione-S-transferase; GGT, gamma glutamyl transpeptidase; TRP2, tyrosinase-related protein 2.
Figure 1 Melanin synthesis (Raper–Mason pathway). Role of glutathione in shifting the equation of melanin synthesis from eumelanin to pheomelanin.