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Clinical, Cosmetic and Investigational Dermatology Volume 16, 2023 - Issue
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CASE REPORT

Onychopathy Following Durvalumab Treatment for Extensive-Stage Small-Cell Lung Cancer: A Case Report

Cuifen Zhang1 the First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of ChinaView further author information
,
Ke Wang1 the First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of ChinaView further author information
,
Hong Zhang1 the First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of ChinaView further author information
,
Jingjing Liu1 the First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of ChinaView further author information
,
Chuangjie Zheng1 the First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of ChinaView further author information
,
Jiahao Tao1 the First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of ChinaView further author information
,
Lizhu Lin2 Cancer Center, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of ChinaView further author information
&
Linzhu Zhai3 Cancer Center, Departments of Radiation Oncology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8507-7220View further author information
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Pages 2429-2432 | Received 21 Jun 2023, Accepted 25 Aug 2023, Published online: 05 Sep 2023

Figures & data

Figure 1 Changes in the nails of patients after treatment with durvalumab at the same time and at different angles. (A) The ten fingers of both hands. (B) The right thumb. (C) The five fingers of the right hand. (D) The five fingers of the left hand.

Figure 1 Changes in the nails of patients after treatment with durvalumab at the same time and at different angles. (A) The ten fingers of both hands. (B) The right thumb. (C) The five fingers of the right hand. (D) The five fingers of the left hand.

Figure 2 Hematoxylin-eosin (HE) staining (A), periodic acid-Schiff staining (PAS) (B), and periodic acid-silver methenamine (PASM) staining (C) of nail keratinocytes and fibrous connective tissue on the bottom of the fingernails.

Figure 2 Hematoxylin-eosin (HE) staining (A), periodic acid-Schiff staining (PAS) (B), and periodic acid-silver methenamine (PASM) staining (C) of nail keratinocytes and fibrous connective tissue on the bottom of the fingernails.

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