Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse^®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series Report

Figures & data

Table 1 Scale for Skin Thickness Evaluation

Skin Thickness	Very Thin	Thin	Normal	Thick	Very Thick
Grade	1	2	3	4	5

Table 2 Grading of the Improvement

Improvement	Absent	Mild	Moderate	High	Very High
Grade	0	1	2	3	4

Table 3 Number of Patients in Different Age Groups Receiving Radiesse^® Divided by Targeted Areas

	Preventive Approach (30–40-Year-Old Patients)	Treatment Approach (40–60-Year-Old Patients)	Treatment Approach (>60-Year-Old Patients)
Face	20 patients	20 patients	10 patients
Neck	10 patients	10 patients	10 patients
Décolletage	10 patients	10 patients	10 patients
Hands	10 patients	10 patients	10 patients

Figure 1 Percentage of patients improved after Radiesse^® injection, as reported in the 3 age groups and in the general population.

Figure 2 A 37-year-old female patient (P.M.) for a preventive approach. (a) Baseline visit. (b) At 8 months after 2 Radiesse^® injection sessions.

Figure 3 A 40-year-old female patient (F.F.) receiving the preventive approach. (a) Baseline visit. (b) At 6 months after one Radiesse^® injection session.

Figure 4 A 42-year-old female patient (M.L.) for the treatment approach. (a) Baseline visit. (b) At 7 months after 2 Radiesse^® injection sessions.

Figure 5 A 48-year-old female patient (A.S.) receiving a treatment approach. (a) Baseline visit. (b) At 10 months after 3 Radiesse^® injection sessions.

Figure 6 A 68-year-old female patient (M.R.) receiving a treatment approach. (a) Baseline visit. (b) At 12 months after 3 Radiesse^® injection sessions.

Figure 7 Neck: This 58-year-old female patient was treated with 1.5 mL of Radiesse^® + 6 mL of saline (final dilution, 1:4). Radiesse^® was injected with a 27 and 30 Gauge needle and a cannula with 50 mm-length and 25 Gauge-diameter (27 and 30 Gauge were both used for convenience and considering the body region). (a) At baseline, her neck skin thickness was thin (grade 2) and the facial skin laxity and wrinkles were moderate (grade 2 on the Merz scale). (b) The improvement reported at 6 months after 3 sessions of Radiesse^® injection was good (grade 3).

Figure 8 Décolletage: This 62-year-old female patient was treated with 1.5 mL of Radiesse^® + 9 mL of saline (final dilution, 1:6). Radiesse^® was delivered via 27 and 30 Gauge needle in a microbolus injection and a cannula with 50 mm-length and 25 Gauge-diameter (27 and 30 Gauge were both used for convenience and considering the body region). (a) At baseline, her décolletage skin thickness was very thin (grade 1) and the décolletage skin laxity and wrinkles were mild (grade 1 on the Merz scale). (b) The improvement reported at 3 months after 6 sessions of Radiesse^® injection was good (grade 3).

Figure 9 Hands: This 50-year-old female patient was treated with 1.5 mL of Radiesse^® + 3 mL of saline (final dilution, 1:2). Radiesse^® was delivered via a cannula with 50 mm-length and 25 Gauge-diameter. (a) At baseline, her hand skin thickness was thin (grade 2) and the hand skin laxity and wrinkles were moderate (grade 2 on the Merz scale). (b) The improvement reported at 3 months after 2 sessions of Radiesse^® injection was very good (grade 4).