Natural Topical Treatment Contributes to a Reduction of Dry Scalp Symptoms in Children

Figures & data

Table 1 Demographic Characteristics of Cohort

Total	N=42
Gender
Male	15 (35.7%)
Female	27 (64.3%)
Race and Ethnicity
NHW	20 (47.6%)
NHB	2 (4.8%)
NHA	3 (7.1%)
H/L	11 (26.2%)
Missing	6 (14.3%)
Household Income
Less than $50,000	3 (7.1%)
$50,000-$99,000	5 (11.9%)
$100,000-$149,000	6 (14.3%)
$150,000-$199,000	5 (11.9%)
$200,000 or more	7 (16.7%)
Declined to answer	3 (7.1%)
Missing	13 (31.0%)
Age
1–4	2 (4.8%)
5–8	9 (21.4%)
10–14	21 (50.0%)
15–17	10 (23.8%)
Scalpdex*
Scalp Symptoms	44.5 (17.8)
Scalp Emotion	45.0 (32.1)
Scalp Function	41.2 (20.8)
Scalp Total	44.2 (21.1)

Notes: *The Scalpdex is a valid instrument that explains the way that patients with scalp dermatitis are affected by symptoms, functioning, and emotions. Items are scored from 0 to 100 (0 indicates never, 25 rarely, 50 sometimes, 75 often, and 100 all the time) and collected at baseline.

Table 2 IGA and TSS Scores Physician Assessments Before and After Treatment

	Baseline Mean (95% CI)	2-Week Exit Mean (95% CI)	Score Difference (95% CI)	Paired t-Test
IGA Score*	3.0 (2.7, 3.3)	2.0 (1.8, 2.2)	1.0 (0.7, 1.2)	p < 0.001
TSS Score**	3.6 (3.1, 4.2)	1.8 (1.3, 2.2)	1.9 (1.4, 2.4)	p < 0.001
Erythema	2.0 (1.7, 2.2)	1.5 (1.3, 1.7)	0.4 (0.2, 0.7)	p < 0.001
Scaling	2.5 (2.2, 2.8)	1.7 (1.5, 2.0)	0.7 (0.5, 1.0)	p < 0.001
Pruritus	2.3 (2.0, 2.5)	1.5 (1.3, 1.7)	0.7 (0.5, 1.0)	p < 0.001

Notes: *The IGA scale is a 5-point assessment ranging from clear (0) to severe disease (4) to assess overall severity of dry scalp. **The TSS assessment averages severity scores for erythema (redness), scaling, and pruritus (itching) using a 4-point scale ranging from none (0) to severe (3).

Table 3 Parent-Reported Dry Scalp Symptom Severity Scores Reported on a Scale of Very Mild (1) to Very Severe (5)

	Baseline Mean (95% CI)	1-Week Midpoint Mean (95% CI)	2-Week Exit Mean (95% CI)	Score Difference (95% CI)	Paired t-Test
Itchiness	3.0 (2.6, 3.4)	2.6 (2.3, 2.9)	2.2 (1.9, 2.5)	0.8 (0.3, 1.2)	p < 0.001
Redness	2.0 (1.6, 2.3)	2.6 (2.2, 3.0)	2.1 (1.8, 2.4)	−0.2 (−0.7, 0.4)	p = 0.747
Sensitivity	2.4 (2.0, 2.8)	2.5 (2.1, 2.9)	2.0 (0.9, 1.7)	0.4 (−0.1, 1.0)	p = 0.052
Dryness	3.7 (3.4, 3.9)	2.9 (2.5, 3.2)	2.0 (1.7, 2.3)	1.7 (1.3, 2.0)	p < 0.001
Irritation	2.7 (2.3, 3.1)	2.6 (2.2, 3.0)	2.0 (1.7, 2.3)	0.7 (0.1, 1.2)	p = 0.008
Flakiness	3.5 (3.2, 3.9)	2.9 (2.5, 3.2)	2.2 (1.9, 2.5)	1.3 (0.9, 1.8)	p < 0.001
Total Mean	16.6 (14.8, 18.4)	16.1 (14.4, 17.9)	12.4 (11.0, 13.7)	4.2 (2.1, 6.3)	p < 0.001