Clinical and Pathological Analysis of 10 Cases of Eosinophilic Pustular Folliculitis

Figures & data

Table 1 Clinical Data and Treatment of EPF Patients

Age (y)	Gender	Course of Disease (y)	Location of Skin Lesions	EPO Count (×109/L)	Pruritus	Treatment
22	Female	0.015	Face	1.16	Present	Indomethacin, glucocorticoid ointment
45	Female	0.4	Face, Trunk	1.54	Present	Prednisone, tretinoin, glucocorticoid ointment
22	Male	0.6	Face	0.82	Present	Minocycline, glucocorticoid ointment
27	Female	0.8	Face	1.07	Present	Indomethacin, glucocorticoid ointment
26	Female	1.5	Face	0.61	Absent	Prednisone, tretinoin, glucocorticoid ointment
25	Male	1	Face, Trunk	1.66	Present	Indomethacin, glucocorticoid ointment
33	Male	10	Face, trunk, hands and feet	1.36	Present	Prednisone, tretinoin, glucocorticoid ointment
35	Male	0.6	Face, Trunk	0.8	Absent	Minocycline, glucocorticoid ointment
27	Female	2	Face, Trunk	1.01	Present	Indomethacin, glucocorticoid ointment
22	Male	0.2	Face	Normal	Absent	Minocycline, glucocorticoid ointment

Figure 1 Clinical pictures: (A–I) Follicular papules with a diameter of about 1–2 mm are seen based on erythema on the face and trunk and expand eccentrically to the periphery in a circular or creeping pattern, and pustules are seen in some patients.

Figure 2 Histopathology: (A) Mild epidermal hyperplasia, lymphocytic and eosinophilic infiltration around the superficial middle dermal vessels and appendages (black arrow), (B) eosinophilic and neutrophilic abscesses seen in local hair follicles (black arrow). (C and D) Acidic mucin deposits around the hair follicle and the hair follicle’s sebaceous glands (black arrow).