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CASE REPORT

Lupus Erythematosus Profundus with Multiple Overlying Cutaneous Ulcerations: A Rare Case

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon show all
Pages 2721-2726 | Received 03 Aug 2023, Accepted 20 Sep 2023, Published online: 28 Sep 2023

Figures & data

Figure 1 Clinical manifestations of LEP in the patient. (A) Multiple cutaneous ulcer and scarring alopecia. (B) Serous crust overlying indurated erythematous plaque on the forehead. (C and D) Clinical improvement after three months of follow up.

Figure 1 Clinical manifestations of LEP in the patient. (A) Multiple cutaneous ulcer and scarring alopecia. (B) Serous crust overlying indurated erythematous plaque on the forehead. (C and D) Clinical improvement after three months of follow up.

Figure 2 Cutaneous ulcers on the vertex and right cheek. (A and B) Prior to treatment. (C and D) After the application of modern wound dressing and topical antibiotic in the first month of follow up. (E and F) After the treatment with oral hydroxychloroquine in the third month of follow up.

Figure 2 Cutaneous ulcers on the vertex and right cheek. (A and B) Prior to treatment. (C and D) After the application of modern wound dressing and topical antibiotic in the first month of follow up. (E and F) After the treatment with oral hydroxychloroquine in the third month of follow up.

Figure 3 Histopathological findings with HE-staining revealed perivascular (red circle), periadnexal (yellow circle), and periadiposal (blue circle) lymphocytic, plasmacytic, and eosinophilic infiltration.

Figure 3 Histopathological findings with HE-staining revealed perivascular (red circle), periadnexal (yellow circle), and periadiposal (blue circle) lymphocytic, plasmacytic, and eosinophilic infiltration.

Figure 4 PAS-staining revealed thickening of the basement membrane pointed with black arrows.

Figure 4 PAS-staining revealed thickening of the basement membrane pointed with black arrows.