The skin landscape in diabetes mellitus. Focus on dermocosmetic management

Figures & data

Table 1 Skin disorders associated with DM

Type 1 DM	Type 2 DM
Alopecia areata	Acanthosis nigricans
Necrobiosis lipoidica	Facial erythrosis
Vitiligo	Pigmented purpuric dermatosis Xerosis

Abbreviation: DM, diabetes mellitus.

Table 2 Correlations reported between some dermatoses and DM complications

Dermatosis	Macroangiopathy	Nephropathy	Retinopathy	Neuropathy
Acanthosis nigricans^Citation81	+	+
Dermopathy^Citation26		+	+	+
Dupuytren’s disease^Citation32			+
Pigmented purpuric dermatosis^Citation17	+			+
Sclerodermoid syndrome^Citation29			+	+

Abbreviation: DM, diabetes mellitus.

Figure 1 Profilometry of the skin surface in a diabetic patient. The sample comprises an untreated xerotic part (A) and a contiguous field (B) treated for 5 days with a urea-based cosmetic formulation.

Note: The amplitude of the skin surface relief is reduced by half on the treated area.

Hermanns-LêTScheenAPiérardGEAcanthosis nigricans associated with insulin resistance; pathophysiology and managementAm J Clin Dermatol20045319920315186199

 PubMed Web of Science ®Google Scholar

ShemerABergmanRLinnSKantorYFriedman-BirnbaumRDiabetic dermopathy and internal complications in diabetes mellitusInt J Dermatol19983721131159542665

 PubMed Web of Science ®Google Scholar

Otto-BuczkowskaEJarosz-ChobotPLimited joint mobility syndrome in patients with diabetesInt J Clin Pract201266433233322420494

 PubMed Web of Science ®Google Scholar

KolbeMKaufmanJLFriedmanJDinersteinCMackenzieJWBoydCDChanges in steady-state levels of mRNAs coding for type IV collagen, laminin and fibronectin following capillary basement membrane thickening in human adult onset diabetesConnect Tissue Res199025177852245601

 PubMed Web of Science ®Google Scholar

YosipovitchGLohKCHockOBMedical pearl: Scleroderma-like skin changes in patients with diabetes mellitusJ Am Acad Dermatol200349110911112833019

 PubMed Web of Science ®Google Scholar