Anhedonia in Acne Vulgaris: A Cross-Sectional Study of 104 Consecutive Acne Patients

Figures & data

Table 1 Demographic Data of Acne Patients

Demographic	Whole group (n=104)	Women (n=69)	Men (n=35)	P
Sex, n (%)
Women	69 (66.3)	NA	NA	NA
Men	35 (33.7)
Acne duration (years) mean ± SD	5.97 ± 4.73	6.71 ± 5.06	4.47 ± 3.61	0.048
Acne in family, n (%)	72 (69.2)	49 (71)	23 (65.7)	NS
IGA, mean ± SD	3.22 ± 0.7	3.10 ± 0.71	3.46 ± 0.61	0.012
Mild acne, n (%)	17 (16.4)	14 (20.3)	3 (8.6)
Moderate acne, n (%)	49 (47.1)	34 (49.3)	15 (42.9)	0.029
Severe acne, n (%)	28 (26.9)	18 (26.1)	10 (28.6)
Very severe acne, n (%)	10 (9.6)	3 (4.3)	7 (20.0)

Abbreviations: N, number of participants; NA, not applicable; SD, standard deviation; NS, non-significant.

Table 2 Correlations Between Different Assessments of Severity of Anhedonia

	SHAPS Total Score	ACIPS Total Score	ACIPS Consummatory	ACIPS Anticipatory	ACPIS-ISI	ACIPS-GSI	ACIPS-SBMC	TEPS Total Score	TEPS Consummatory	TEPS Anticipatory
SHAPS Total score	NA	r=0.370	r=−0.346	r=−0.346	r=−0.422	NS	r=−0.318	r=−0.448	r=−0.486	r=−0.320
		p<0.001	p<0.001	p<0.001	p<0.001		p<0.001	p<0.001	p<0.001	p<0.001
ACIPS Total Score	r=0.370	NA	r=0.953	r=0.902	r=0.928	r=0.803	r=0.903	r=0.678	r=0.707	r=0.496
	p<0.001		p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001
ACIPS consummatory	r=−0.346	r=0.953	NA	r=0.738	=0.851	r=0.824	r=0.872	r=0.643	r=0.468	r=0.671
	p<0.001	p<0.001		p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001
ACIPS anticipatory	r=−0.346	r=0.902	r=0.738	NA	r=0.891	r=0.639	r=0.809	r=0.603	r=0.450	r=0.620
	p<0.001	p<0.001	p<0.001		p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001
ACPIS-ISI	r=−0.422	r=0.928	r=0.851	r=0.891	NA	r=0.646	r=0.748	r=0.643	r=0.493	r=0.647
	p<0.001	p<0.001	p<0.001	p<0.001		p<0.001	p<0.001	p<0.001	p<0.001	p<0.001
ACIPS-GSI	NS	r=0.803	r=0.824	r=0.639	r=0.646	NA	r=0.630	r=0.538	r=0.380	r=0.580
		p<0.001	p<0.001	p<0.001	p<0.001		p<0.001	p<0.001	p<0.001	p<0.001
ACIPS-SBMC	r=−0.318	r=0.903	r=0.872	r=0.809	r=0.748	r=0.630	NA	r=0.568	r=0.408	r=0.608
	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001		p<0.001	p<0.001	p<0.001
TEPS total score	r=−0.448	r=0.678	r=0.643	r=0.603	r=0.643	r=0.538	r=0.568	NA	r=0.849	r=0.912
	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001		p<0.001	p<0.001
TEPS consummatory	r=−0.486	r=0.496	r=0.468	r=0.450	r=0.493	r=0.380	r=0.408	r=0.849	NA	r=0.589
	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001		p<0.001
TEPS anticipatory	r=−0.320	r=0.707	r=0.671	r=0.620	r=0.647	r=0.580	r=0.608	r=0.912	r=0.589	NA
	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001	p<0.001

Abbreviations: SHAPS, Snaith-Hamilton Pleasure Scale; ACIPS, Anticipatory and Consummatory Interpersonal Pleasure Scale; ACIPS ISI, ACIPS intimate social interactions; ACIPS-GSI, ACIPS group social interactions; ACIPS-SBMC, ACIPS social bonding and making connections; TEPS, Temporal Experience of Pleasure Scale; NA, not applicable; NS, non-significant; r, spearman coefficient.

Table 3 Differences in Anhedonia Severity Between Sexes

Anhedonia Assessment	Whole Group (n=104)	Women (n=69)	Men (n=35)	P
SHAPS, mean ± SD	1.63 ± 2.69	1.26 ± 2.36	2.39 ± 3.18	0.049
SHAPS Anhedonia, n(%)	21 (20.19)	9 (13.04)	12 (34.29)	0.007
ACIPS Total, mean ± SD	80.17 ± 13.89	81.04 ± 13.84	78.33 ± 14.03	NS
ACIPS consummatory, mean ± SD	47.25 ± 8.94	47.81 ± 8.95	46.09 ±8.94	NS
ACIPS anticipatory, mean ± SD	32.91 ± 5.83	33.23 ± 5.87	32.24 ± 5.77	NS
ACIPS-ISI, mean ± SD	4.64 ± 0.82	4.75 ± 0.8	4.42 ± 0.84	0.048
ACIPS-GSI, mean ± SD	5.02 ± 1.0	5.04 ± 1.06	4.98 ± 0.9	NS
ACIPS-SBMC, mean ± SD	4.59 ± 0.96	4.58 ± 0.94	4.62 ± 1.02	NS
TEPS Total, mean ± SD	80.76 ± 15.58	82.74 ± 14.77	76.82 ± 16.6	NS
TEPS anticipatory, mean ± SD	44.9 ± 9.75	46.28 ± 9.43	42.15 ± 9.93	NS
TEPS consummatory, mean ± SD	35.86 ± 7.49	36.46 ± 7.03	34.68 ± 8.32	NS

Abbreviations: SHAPS, Snaith-Hamilton Pleasure Scale; ACIPS, Anticipatory and Consummatory Interpersonal Pleasure Scale; ACIPS ISI, ACIPS intimate social interactions; ACIPS-GSI, ACIPS group social interactions; ACIPS-SBMC, ACIPS social bonding and making connections; TEPS, Temporal Experience of Pleasure Scale; NS, non-significant.

Table 4 Correlations of Different Assessments of Anhedonia with Clinical Severity of Acne

	IGA	Acne duration (years)
SHAPS Total score	r=−0.205	r=−0.216
	p=0.038	p=0.032
ACIPS Total Score	r=−0.222	NS
	p=0.026
ACIPS consummatory	r=−0.243	NS
	p=0.015
ACIPS anticipatory	NS	NS
ACPIS-ISI	r=−0.215	NS
	p=0.032
ACIPS-GSI	NS	NS
ACIPS-SBMC	NS	NS
TEPS total score	NS	NS
TEPS consummatory	NS	r=0.230
		p=0.021
TEPS anticipatory	NS	NS

Abbreviations: SHAPS, Snaith-Hamilton Pleasure Scale; ACIPS, Anticipatory and Consummatory Interpersonal Pleasure Scale; ACIPS ISI, ACIPS intimate social interactions; ACIPS-GSI, ACIPS group social interactions; ACIPS-SBMC, ACIPS social bonding and making connections; TEPS, Temporal Experience of Pleasure Scale; NS, non-significant; IGA, Investigator Global Assessment.

Data Sharing Statement

Data available on request.