Figures & data
Table 1 List of selected tissue biomarkers in melanoma
Figure 1 MiTF accurately enumerates the melanocytes in the epidermis of chronic sun exposed skin and in lesions of lentigo maligna.
Abbreviations: H&E, hematoxylin and eosin; IHC, immunohistochemistry.
![Figure 1 MiTF accurately enumerates the melanocytes in the epidermis of chronic sun exposed skin and in lesions of lentigo maligna.](/cms/asset/139206c7-6ccb-4e28-84f8-2fc3fd9b3d63/dcci_a_49578_f0001_c.jpg)
Figure 2 Evaluation of bread-loafed cross-sections of peripheral margins allows for comparison of the background increased density of melanocytes, reflective of chronic sun damage (at the periphery), with area of lentigo maligna (at the center).
![Figure 2 Evaluation of bread-loafed cross-sections of peripheral margins allows for comparison of the background increased density of melanocytes, reflective of chronic sun damage (at the periphery), with area of lentigo maligna (at the center).](/cms/asset/7147e494-98b5-4ba4-bb0a-7ef99ebc4057/dcci_a_49578_f0002_c.jpg)
Figure 3 Sox10 identifies rare tumor cells in heavily regressed areas of melanoma.
Abbreviations: H&E, hematoxylin and eosin; IHC, immunohistochemistry.
![Figure 3 Sox10 identifies rare tumor cells in heavily regressed areas of melanoma.](/cms/asset/a9a5e2b3-2567-4851-b2ec-c71a9341464d/dcci_a_49578_f0003_c.jpg)
Figure 4 Detection and confirmation of lymphovascular invasion.
Abbreviations: H&E, hematoxylin and eosin; IHC, immunohistochemistry; LVI, lymphovascular invasion.
![Figure 4 Detection and confirmation of lymphovascular invasion.](/cms/asset/2fc9d013-e32f-4cf1-b8d5-726e1af57d1c/dcci_a_49578_f0004_c.jpg)
Figure 5 Detection of mitotic figures and G2+ tumor nuclei with histone markers.
Abbreviation: IHC, immunohistochemistry.
![Figure 5 Detection of mitotic figures and G2+ tumor nuclei with histone markers.](/cms/asset/b0a728ed-1d0e-48f5-96cf-664649d079de/dcci_a_49578_f0005_c.jpg)
Figure 6 Immunohistochemcial evaluation of BRAFV600E mutation status in melanoma.
Abbreviations: AEC, 3-amino-9-ethylcarbazole; DAB, diaminobenzidine; H&E, hematoxylin and eosin; IHC, immunohistochemistry.
![Figure 6 Immunohistochemcial evaluation of BRAFV600E mutation status in melanoma.](/cms/asset/e87a62bd-b7d6-4ea2-b077-2053cba0a6b8/dcci_a_49578_f0006_c.jpg)
Figure 7 Immunohistochemcial evaluation of BAP-1 and BRAFV600E status in melanocytic lesions.
Abbreviations: H&E, hematoxylin and eosin; IHC, immunohistochemistry.
![Figure 7 Immunohistochemcial evaluation of BAP-1 and BRAFV600E status in melanocytic lesions.](/cms/asset/f72c8275-999f-4b01-8c44-17ca5ac87ead/dcci_a_49578_f0007_c.jpg)