Eosinophilic esophagitis: early diagnosis is the key

Figures & data

Table 2 Symptoms of EoE in children and adults

Children	Adults
Feeding difficulties	Decreased appetite
Food aversion	Heartburn
Decreased appetite	Early satiaety
Heartburn	Chest pain
Chest pain	Nausea
Abdominal pain	Regurgitation
Gagging	Uncommon
Nausea	Sialorrhea
Regurgitation	Vomiting
Vomiting	Dysphagia
Slow growth/failure to thrive/weight loss	Food impaction
Cough after eating
Dysphagia
Food impaction

Table 3 Questions to ask to elicit symptoms of EoE

Does the food get stuck when you eat?

Does it take longer than others to eat?

Do you need to cut food into small pieces?

Do you need to drink always with meals?

Do you eat steak? Do you eat crusty bread?

Do you need to make the crusty bread softer?

Do you need to cut steak in small pieces?

Do you have to get reminded to chew a lot?

Table 1 Atopy as a risk factor for eosinophilic esophagitis

	Number of patients with EoE	Atopy	Asthma	AR	AD	IgE-FA	Anaphylaxis to foods
General population	NA	30%	8.5%	25%	10%	10%	0.2%
Spergel et al^Citation17	620	NA	50%	61%	21%	50%	10%
Ass’ad et al^Citation18	89	79%	39%	30%	19%	75%	NA
Capucilli P et al^Citation19	428	NA	59%	60%	18%	NA	NA

Abbreviations: EoE, eosinophilic esophagitis; AD, atopic dermatitis; IgE-FA, IgE-mediated food allergies, AR, Allergic Rhinitis

Spergel JM, Brown-Whitehorn TF, Beausoleil JL. 14 years of eosinophilic esophagitis: clinical features and prognosis. J Pediatr Assa

 Google Scholar

Assa'ad AH, Putnam PE, Collins MH. Pediatric patients with eosinophilic esophagitis: an 8-year follow-up. J Pediatr Gastroenterol Nutr. 2009;48(1):30–36.19172120

 PubMed Web of Science ®Google Scholar

Capucilli P, Cianferoni A, Grundmeier RW, Spergel JM. Comparison of comorbid diagnoses in children with and without eosinophilic esophagitis in a large population. Ann Allergy Asthma Immunol. 2018;121(6):711–716.30194971

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