Cardiovascular Risk in Individuals with Inflammatory Bowel Disease

Figures & data

Table 1 Clinical Variables and Risk Factors for Cardiovascular Disease in the IBD and Control Groups

	IBD Group (n=52)	Control Group (n=37)	P-value
Age (y)	49.2±11.4	45.5±10.1	0.117
Sex, female	27 (51.9)	22 (59.4)	0.625
Active smoking	2 (3.8)	6 (16.2)	0.062
Diabetes	7 (13.5)	3 (8.1)	0.513
High blood pressure	8 (15.4)	6 (16.2)	0.850
Dyslipidemia	2 (3.8)	5 (13.5)	0.122
Systolic blood pressure (mmHg) Diastolic blood pressure (mmHg)	12 (11 - 13) 8 (7 - 9)	12 (11.5 - 13) 8 (7 - 8)	0.897 0.927
Total cholesterol (mg/dL)	188±43	195±37	0.434
HDL-cholesterol (mg/dL)	47.5 (39 - 59)	46 (41 - 53.5)	0.683
LDL-cholesterol (mg/dL)	108±37	119±27.6	0.136
Fasting glucose (mg/dL)	95 (86.2 - 107.3)	86 (79 - 100)	0.041
Triglycerides (mg/dL)	126.5 (89.5 - 181.5)	123 (89 - 182)	0.930
Carotid intima-media thickness (mm)	0.69±0.12	0.63±0.12	0.031
Presence of atherosclerotic plaque	13 (25)	2 (5.4)	0.032
Moderate and high cardiovascular risk according to the Framingham risk score	16 (30.8)	5 (13.5)	0.102

Note: Data expressed as n (%), mean±SD, or median and quartiles (Q1–Q3).

Abbreviations: HDL-cholesterol, high-density lipoprotein cholesterol; LDL-cholesterol, low-density lipoprotein cholesterol.

Table 2 Logistic Regression for the Presence of Atherosclerotic Plaque and Linear Regression for Carotid Intima-Media Thickness in the IBD Group

Presence of Atherosclerotic Plaque
	OR	95% CI	p-value
Univariate	5.83	1.229–27.679	0.026
Adjusted*	6.45	1.035–40.216	0.046
Carotid Intima-Media Thickness
	Coef	Std. Error	p-value
Univariate	0.0552	0.0252	0.031
Adjusted*	0.0314	0.0230	0.176

Notes: *Adjusted value for age, sex, smoking status, glucose, LDL-cholesterol, triglycerides, and body mass index.

Abbreviations: OR, odds ratio; CI, confidence interval.