Gut Dysbiosis and Increased Intestinal Permeability Drive microRNAs, NLRP-3 Inflammasome and Liver Fibrosis in a Nutritional Model of Non-Alcoholic Steatohepatitis in Adult Male Sprague Dawley Rats [Erratum]

Figures & data

Table 5 Correlations between NASH markers and microbiota composition

Variables^#	Inflammatory Response		Intestinal Permeability		Microbiota composition
	Index TNF-α/IL-10 (pg/mg)	Index IL-1β/IL-10 (pg/mg)	Ocln	F11r (JAM-1)
NAFLD scoring	0.751**	0.832**	-.719**	-.525*	0.694**
Index TNF-α/IL-10 (pg/mg)		0.729**	-.463*	-.208	0.234*
Index IL-1β/IL-10 (pg/mg)			-.457*	-.361	0.522*
Ocln				0.722**	0.090
F11r (JAM-1)					0.146*

Notes: ^#Variables was represented for Spearman’s correlation coefficient. Moderate (0.3 < r < 0.6 - blue) and strong (0.6 < r < 0.9 - green) correlation of Spearman’s. **Correlation is significant at the 0.01 level. *Correlation is significant at the 0.05 level.

Abbreviations: IL, interleukin; JAM, junctional adhesion molecule; NAFLD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis; Ocln, occluding; TNF, tumor necrosis factor.