A comparative analysis of clinical outcomes and disposable costs of different catheter ablation methods for the treatment of atrioventricular nodal reentrant tachycardia

Figures & data

Table 1 Baseline and postablation patient characteristics

Characteristics	Conventional ablation (n=60)	RMN ablation (n=67)	Cryoablation (n=56)	p-value
Age (years)	51.2±15.7	48.7±19.2	47.6±18.6	NS
Male (%)	30	36	23	NS
HTN (%)	55	49	37.5	NS
CAD (%)	15	13	13	NS
Cardiomyopathy (%)	16.7	8.9	7.1	0.01
Typical AVNRT (%)	91.7	79.1	83.9	NS
Patients with documented AVNRT recurrence postablation (n)	2	1	9	0.003
Patients with complete heart block postablation (n)	0	0	0	NS

Note: Data are presented as mean ± SD.

Abbreviations: AVNRT, atrioventricular nodal reentrant tachycardia; CAD, coronary artery disease; HTN, hypertension; RMN, remote magnetic navigation; NS, nonsignificant.

Table 2 Baseline patient demographic data

Demographics	Conventional ablation (n=60)	RMN ablation (n=67)	Cryoablation (n=56)	p-value
White (%)	71.6	70.1	76.8	NS
Black (%)	26.7	26.9	23.2	NS
Asian (%)	1.7	1.5	0	NS
Native American (%)	0	1.5	0	NS

Abbreviations: RMN, remote magnetic navigation; NS, nonsignificant.

Table 3 Results of univariate logistic regression using recurrent AVNRT as the dependent variable

Variable	Odds ratio (95% CI)	p-value
Age (years)	1.00 (0.96,1.03)	NS
Gender	0.84 (0.24, 2.92)	NS
Presence of hypertension	0.52 (0.15, 1.8)	NS
History of CAD	1.23 (0.25, 5.98)	NS
Cardiomyopathy (LVEF <45%)	2.85 (0.70, 11.5)	NS
Type of AVNRT	1.96 (0.49, 7.74)	NS
Conventional manual ablation (RF energy)	0.39 (0.08, 1.85)	NS
RMN-guided ablation (RF energy)	0.15 (0.018, 1.15)	NS
Cryoablation	7.75 (2.01, 29.8)	0.003

Abbreviations: AVNRT, atrioventricular nodal reentrant tachycardia; CAD, coronary artery disease; HTN, hypertension; LVEF, left ventricular ejection fraction; RF, radiofrequency; RMN, remote magnetic navigation; NS, nonsignificant.

Table 4 Disposable cost-comparison analysis of the different methods of catheter ablation of AVNRT

Method of ablation	Disposable cost per case (USD)	Mean cost per modality (USD)
CONV 4 mm/CARTO™	2124	2340
CONV 4 mm/ESI™	2555
CRYO 6 mm/ESI™	3515	3515
CRYO 8 mm/ESI™	3995
RMN 4 mm/CARTO™	4992	5190
RMN 3.5 mm OIC/CARTO™	5387

Notes: Measurements refer to catheter tip size. ESI™ (Abbott Medical, Sylmar, CA, USA) and CARTO™ (Biosense Webster, Irvine, CA, USA) are 3-D mapping systems.

Abbreviations: AVNRT, atrioventricular nodal reentrant tachycardia; CONV, conventional; CRYO, cryoablation; OIC, open irrigation catheter; RMN, remote magnetic navigation; USD, US dollars; 3-D, three-dimensional.