Figures & data
Table 1 Costs of drugs, AEs and total joint replacement used in CEA and BIA
Table 2 Base case ICERs – hylan G-F 20 1×6 mL
Table 3 Base case ICERs – hylan G-F 20 3×2 mL
Table 4 Base case ICERs – hylan G-F 20 1×2 mL
Table 5 Scenario analysis results
Figure 1 (A) CEA plane for hylan G-F 20 1×6 mL vs acetaminophen. (B) CEA plane for hylan G-F 20 1×6 mL vs NSAIDs. (C) CEACs hylan G-F 20 1×6 mL vs acetaminophen. (D) CEACs hylan G-F 20 1×6 mL vs NSAIDs.
Figure 2 (A) CEA plane for hylan G-F 20 3×2 mL vs acetaminophen. (B) CEA plane for hylan G-F 20 3×2 mL vs NSAIDs. (C) CEACs hylan G-F 20 3×2 mL vs acetaminophen. (D) CEACs hylan G-F 20 3×2 mL vs NSAIDs.
Figure 3 (A) CEA plane for hylan G-F 20 1×2 mL vs acetaminophen. (B) CEA plane for hylan G-F 20 1×2 mL vs NSAIDs. (C) CEACs hylan G-F 20 1×2 mL vs acetaminophen. (D) CEACs hylan G-F 20 1×2 mL vs NSAIDs.
Table 6 Budget impact for hylan G-F 1×6 mL (knee)
Table 7 Budget impact for hylan G-F 20 3×2 mL (knee)
Table 8 Budget impact for hylan G-F 20 1×2 mL (hip)
Table S1 Drugs and cost used in cost-effectiveness and budget impact
Table S2 COX2 and proton pump inhibitor (PPI) costs used in budget impact