Health expenditure comparison of extended-release metoprolol succinate and immediate-release metoprolol tartarate

Figures & data

Figure 1 Patient selection criteria of MT and MS cohorts.

Abbreviations: MEPS, Medical Expenditure Panel Survey; MS, metoprolol succinate; MT, metoprolol tartarate.

Table 1 Demographic characteristics of the MT and MS cohorts

	MT (n = 291)	MS (n = 291)	P-value
Gender, n (%)
Male	138 (47.42)	138 (47.42)	1.0000
Female	153 (52.58)	153 (52.58)	1.0000
Age group, n (%)
0–40 years	12 (4.12)	15 (5.15)	0.5544
41–65 years	140 (48.11)	147 (50.51)	0.5617
>65 years	139 (47.77)	129 (44.34)	0.4056
Income, n (%, USD)
<20,000	86 (29.55)	78 (26.80)	0.4610
20,000–49,999	92 (31.61)	97 (33.33)	0.6581
50,000–100,000	80 (27.49)	80 (27.49)	1.0000
>100,000	33 (11.35)	36 (12.38)	0.7005
Race, n (%)
White	209 (71.82)	207 (71.13)	0.8543
African-American	65 (22.33)	61 (20.96)	0.6873
Other minorities	17 (5.85)	23 (7.91)	0.3256
Ethnicity, n (%)
Hispanics	40 (13.74)	43 (14.77)	0.7221
Non-Hispanics	251 (86.26)	248 (85.23)	0.7221
Insurance status, n (%)
Public insurance	107 (36.77)	112 (38.48)	0.6688
Other insurance	168 (57.73)	161 (55.32)	0.5583
Uninsured	16 (5.50)	18 (6.20)	0.7237
Employment status, n (%)
Employed	88 (30.24)	96 (32.99)	0.4757
Unemployed	203 (69.76)	195 (67.01)	0.4757
Charlson’s comorbidity index	2.2	2.3	0.734

Abbreviations: MS, metoprolol succinate; MT, metoprolol tartarate.

Figure 2 Health expenditure comparison and cost comparison of MT and MS.

Abbreviations: AWP, average wholesale price; MS, metoprolol succinate; MT, metoprolol tartarate; Rx, prescription.

Table 2 Factors affecting differences in total healthcare and total Rx expenditures

Variable	Total health care expenditure		Total Rx expenditure
	Estimate	P-value	Estimate	P-value
Intercept	2.1153	<0.0001	1.8548	<0.0001
Cohort
MT	Reference	–	Reference	–
MS	0.0148	0.2319	0.0366	0.0208
Comorbidity index	−0.0006	0.7971	−0.0002	0.9526
Gender
Female	Reference	–	Reference	–
Male	−0.0052	0.6904	0.0101	0.5480
Age (years)
0–40	Reference	–	Reference	–
41–65	0.0232	0.4461	0.0895	0.0214
>65	0.0499	0.1201	0.1036	0.0113
Income (USD)
<20,000	Reference	–	Reference	–
20,000–49,999	−0.0269	0.1033	−0.0183	0.3865
50,000–100,000	−0.0016	0.9321	0.0043	0.8574
>100,000	−0.0064	0.7930	−0.0380	0.2261
Race
White	Reference	–	Reference	–
African-American	0.0011	0.9482	−0.0178	0.3939
Other minorities	−0.0318	0.2064	−0.0020	0.9505
Ethnicity
Non-Hispanic	Reference	–	Reference	–
Hispanic	−0.0141	0.4619	−0.0112	0.6484
Insurance status
Uninsured	Reference	–	Reference	–
Public insurance	0.0185	0.5331	0.0667	0.0776
Private insurance	0.0253	0.3811	0.0537	0.1462
Employment status
Unemployed	Reference	–	Reference	–
Employed	−0.0940	<0.0001	−0.0886	<0.0001

Abbreviations: MS, metoprolol succinate; MT, metoprolol tartarate; Rx, prescription.