Does severity of dermatochalasis in aging affect corneal biomechanical properties?

Figures & data

Table 1 Some descriptive values for the groups in this study

Descriptive parameters	Group 1	Group 2	Group 3	Group 4	P-value*
Sex
Male (n)	4	6	4	8	P1=0.23
Female (n)	21	15	23	14
Age, years
Mean ± SD	48.7±13.8	50.9±11.1	54.2±10.7	56.8±9.7	P2=0.084
Range, minimum–maximum	18–81	28–72	29–70	39–83
Spherical equivalents, diopters
Mean ± SD	0.23±1.01	0.3±0.89	0.25±0.9	0.36±1.06	P3=0.96
Range, minimum/maximum	−2.5/2.0	−1.5/1.0	−1.0/2.0	−2.0/1.75
BCVA
Mean ± SD	0.96±0.12	0.97±0.1	0.97±0.09	0.93±0.13	P4=0.25
Range, minimum/maximum	1/1	1/1	1/1	1/1
CCT, µm
Mean ± SD	556.2±38.6	554.8±25.6	532.0±37.0	545.1±33.3	P5=0.052
Range, minimum/maximum	508/655	517/618	478/621	483/599

Notes:

* The value of P₁ was obtained with the chi-square test. P₄ was gained with Kruskal–Wallis test. The P₂-, P₃-, and P₅-values were calculated using one-way ANOVA test.

Abbreviations: BCVA, best-corrected visual acuity; CCT, central corneal thickness; ANOVA, analysis of variance.

Table 2 The descriptive statistics of IOP_GAT, IOP_cc, CH, and CRF

	Minimum	Maximum	Mean	SD
Group 1 (n=25)
IOPGAT, mmHg	11	20	16.24	2.29
IOPcc, mmHg	12.1	22.6	16.05	2.59
CH	8.3	12.6	10.02	1.35
CRF	7	12	9.98	1.45
Group 2 (n=21)
IOPGAT, mmHg	11	23	15.90	3.06
IOPcc, mmHg	11.3	26.8	18.16	3.62
CH	6.9	13.9	9.67	1.59
CRF	8	15	10.26	1.62
Group 3 (n=27)
IOPGAT, mmHg	10	21	15.70	2.47
IOPcc, mmHg	11.4	22.7	17.04	2.98
CH	7.5	13.2	9.80	1.34
CRF	8	13	10.06	1.44
Group 4 (n=22)
IOPGAT, mmHg	12	22	15.91	2.95
IOPcc, mmHg	13.4	22.5	17.42	2.66
CH	7.4	11.2	9.65	1.01
CRF	7	13	10.01	1.64

Abbreviations: IOP, intraocular pressure; IOP_GAT, IOP measurement with calibrated Goldmann applanation tonometry; IOP_cc, corneal-compensated IOP; CH, corneal hysteresis; CRF, corneal resistance factor.

Table 3 The correlation analysis of all groups

	Statistical results	IOPGAT	IOPcc	CH	CRF
Group 1
IOPGAT	R	1	0.20	0.34	0.52
	P	–	0.33	0.09	0.007
IOPcc	R	0.20	1	−0.49	0.06
	P	0.33	–	0.013	0.76
CH	R	0.34	−0.49	1	0.83
	P	0.09	0.013	–	0.00
CRF	R	0.52	0.06	0.83	1
	P	0.00	0.76	0.00	–
Group 2
IOPGAT	R	1	0.38	0.41	0.78
	P	–	0.08	0.05	0.00
IOPcc	R	0.38	1	−0.52	0.15
	P	0.08	–	0.015	0.50
CH	R	0.41	−0.52	1	0.76
	P	0.056	0.015	–	0.00
CRF	R	0.78	0.15	0.76	1
	P	0.000	0.509	0.00	–
Group 3
IOPGAT	R	1	0.27	0.44	0.68
	P	–	0.17	0.02	0.00
IOPcc	R	0.27	1	−0.47	0.15
	P	0.17	–	0.011	0.42
CH	R	0.44	−0.47	1	0.78
	P	0.02	0.011	–	0.00
CRF	R	0.68	0.15	0.78	1
	P	0.000	0.42	0.00	–
Group 4
IOPGAT	R	1	0.71	0.18	0.54
	P	–	0.00	0.41	0.008
IOPcc	R	0.71	1	0.12	0.66
	P	0.000	–	0.57	0.001
CH	R	0.18	0.12	1	0.82
	P	0.41	0.57	–	0.00
CRF	R	0.54	0.66	0.82	1
	P	0.008	0.001	0.00	–

Notes: Data in bold indicates statistical significance. “–” Indicates not applicable.

Abbreviations: IOP, intraocular pressure; IOP_GAT, IOP measurement with calibrated Goldmann applanation tonometry; IOP_cc, corneal-compensated IOP; CH, corneal hysteresis; CRF, corneal resistance factor.