Figures & data
Table 1 Demographic and baseline characteristics of the study population (N=186)
Figure 1 Changes in average pain severity score measured on an 11-point NRS during the 60-day treatment with OXN-PR.
Notes: *P=0.02 T60 vs T30 result; **P<0.0001 T30 vs T15 result.
Abbreviations: NRS, numerical rating scale; OXN-PR, prolonged-release oxycodone/naloxone; T0, baseline; T15, day 15; T30, day 30; T60, day 60.
![Figure 1 Changes in average pain severity score measured on an 11-point NRS during the 60-day treatment with OXN-PR.Notes: *P=0.02 T60 vs T30 result; **P<0.0001 T30 vs T15 result.Abbreviations: NRS, numerical rating scale; OXN-PR, prolonged-release oxycodone/naloxone; T0, baseline; T15, day 15; T30, day 30; T60, day 60.](/cms/asset/e3bf6924-80a4-4b26-b27b-db381698e8ae/dcia_a_105821_f0001_c.jpg)
Figure 2 Waterfall image of individual changes in pain severity after 30 days of treatment with OXN-PR.
Abbreviation: OXN-PR, prolonged-release oxycodone/naloxone.
![Figure 2 Waterfall image of individual changes in pain severity after 30 days of treatment with OXN-PR.](/cms/asset/ee21bd88-0f0c-4a82-a03e-e24afb0b8486/dcia_a_105821_f0002_c.jpg)
Figure 3 Changes in bowel function according to the Bowel Function Index during the 60-day treatment with OXN-PR.
Abbreviations: OXN-PR, prolonged-release oxycodone/naloxone; T0, baseline; T15, day 15; T30, day 30; T60, day.
![Figure 3 Changes in bowel function according to the Bowel Function Index during the 60-day treatment with OXN-PR.](/cms/asset/4cadd14c-86f0-4167-bb6e-65e0da58870d/dcia_a_105821_f0003_c.jpg)
Figure 4 Changes in (A) average pain severity score measured on an 11-point NRS and (B) bowel function in the age subgroups 75–85 years (n=148) and >85 years (n=38).
Abbreviations: NRS, numerical rating scale; T0, baseline; T15, day 15; T30, day 30; T60, day 60.
![Figure 4 Changes in (A) average pain severity score measured on an 11-point NRS and (B) bowel function in the age subgroups 75–85 years (n=148) and >85 years (n=38).](/cms/asset/f40fffc2-932e-4a2a-b462-71a06c61cd23/dcia_a_105821_f0004_c.jpg)