The prevalence of lacunar infarct decreases with aging in the elderly: a case-controlled analysis

Figures & data

Table 1 The distribution of LI by different age range and sex

Sex	Age distribution (years)							N	P-value	F	R^2
	10–29	30–39	40–49	50–59	60–69	70–79	80–100
Total	500	500	500	500	500	500	500	3,500
LI (M + F)	1	6	67	168	394	315	80	1,032	0.0269	8.473	0.1745
	0.2%	1.2%	13.4%	33.6%	78.8%	63%	16%
Male (LI)	1	5	41	102	179	170	46	544	0.0295	8.077	0.2891
	0.2%	1%	8.2%	20.4%	35.8%	34%	2.3%
Female (LI)	0	1	27	66	215	145	34	488	0.0485	6.739	0.2825
	0.0%	0.2%	1.35%	3.3%	43%	29%	1.7%

Abbreviations: F, female; LI, lacunar infarct; M, male.

Figure 1 Age distribution of LI patients.

Notes: The prevalence of LI varies by age group, with the highest prevalence of collected cases occurring in age between 60 years and 69 years. (A) Trend of age distribution. (B) Distribution of LI by different age.
Abbreviation: LI, lacunar infarct.

Table 2 The relationship between risk factors and the prevalence of LI on the basis of age (one-way analysis of variance)

Risk factors	Age distribution (years)							P-value	F	R^2
	10–29	30–39	40–49	50–59	60–69	70–79	80–100
Total	500	500	500	500	500	500	500
Hypertension	0	3	39	115	277	239	0	0.3064	1.486	0.5602
	0	0.60	1.80	23	55.40	47.80	0
Diabetes	0	1	11	38	59	52	16	0.4208	1.158	0.4981
	0	0.2	2.2	7.6	11.8	10.4	3.2
Cardiovascular diseases	0	0	4	9	32	62	24	0.3130	1.464	0.5564
	0	0	0.8	1.8	6.4	12.4	4.8
Cerebral infarct	0	0	9	23	40	57	9	0.3537	1.336	0.5338
	0	0	1.8	4.6	8	11.4	1.8
Smoking	0	1	27	49	94	83	21	0.4217	1.155	0.4976
	0	0.2	5.4	9.8	18.8	16.6	4.2
Drinking	0	4	31	80	112	83	18	0.4290	1.138	0.4938
	0	0.8	6.2	16	22.4	16.6	3.6

Abbreviation: LI, lacunar infarct.

Table 3 The prevalence of LI according to risk factors on the basis of age (one-way analysis of variance)

Risk factors	Age distribution (years)							P-value	F	R^2
	10–29	30–39	40–49	50–59	60–69	70–79	80–100
Hypertension	0	3	39	115	277	239	0	0.0006	5.209	0.4717
Diabetes	0	1	11	38	59	52	16
CVD	0	0	4	9	32	62	24
Cerebral infarct	0	0	9	23	40	57	9
Smoking	0	1	27	49	94	83	21
Drinking	0	4	31	80	112	83	18
95% confidence interval	–	−31.55 to −5.788	−69.97 to 5.635	−140.1 to 40.07	−98.79 to 111.5	16.01 to 146.7
P-value (t-test)	–	0.0090	0.0872	0.2444	0.8959	0.0196
P-value (F-test)	–	0.0002	0.0424	0.0875	0.6053	0.0003

Note: “–” indicates not specified.

Abbreviations: CVD, cardiovascular disease; LI, lacunar infarct.