Development and validation of the Medication Regimen Simplification Guide for Residential Aged CarE (MRS GRACE)

Figures & data

Figure 1 Agreement and ability to (A) simplify and (B) decrease regular administration times for residents in the validation sample, stratified by number of administration times per day for regular medications.

Table 1 Frequency of each type of recommendation to simplify medication charts

Type of recommendation to simplify	Pharmacist A n=60 (%)	Pharmacist B n=46 (%)	Example
Change of an administration time with no change in dose at each administration time	47 (78.3)	34 (73.9)	Atorvastatin 20 mg 1 evening to 1 tea
Change of an administration time with a change in dose at an administration time (same total daily dose)	13 (21.7)	12 (26.1)	Spironolactone 25 mg 1 breakfast and 1 mid-afternoon to 2 breakfast
Change in strength of formulation given (same total daily dose)	0 (0)	3 (6.5)	Sertraline 50 mg 1 breakfast and 1 evening to 100 mg 1 breakfast
Change of formulation	7 (11.7)	4 (8.7)	Paracetamol 500 mg IR 2 breakfast, 2 lunch, 2 tea and 2 evening to paracetamol 665 mg MR 2 breakfast, 2 mid-afternoon and 2 evening
Total unique recommendations	60	46

Note: Recommendations could have been counted in more than one category if applicable.

Abbreviations: IR, immediate release; MR, modified release.

Figure 2 Agreement and ability to simplify regular medications in medication regimens of residents in the validation sample, categorized by Anatomic Therapeutic Chemical (ATC) main group classification.

Abbreviations: A, alimentary tract and metabolism; B, blood and blood forming organs; C, cardiovascular system; D, dermatologicals; G, genito-urinary system and sex hormones; H, systemic hormonal preparations, excluding sex hormones and insulins; J, anti-infectives for systemic use; L, antineoplastic and immunomodulating agents; M, musculoskeletal system; N, nervous system; R, respiratory system; S, sensory organs; V, various.

Figure S1 The Medication Regimen Simplification Guide for Residential Aged CarE (MRS GRACE): explanatory statement and specific instructions.